SCHEMBL2947083

SCHEMBL2947083

O=S(=O)(c1ccc(Cl)cc1)c1ccccc1-c1ccccc1S(=O)(=O)c1ccc(Cl)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.60
CYP3A4 P08684 1/20 0.60
MAPK1 P28482 1/20 0.60
PTGS2 P35354 2/20 0.52
PTGS1 P23219 1/20 0.52
CNR2 P34972 1/20 0.51
KDM4E B2RXH2 2/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
PKM P14618 1/20 0.50
HSD11B1 P28845 3/20 0.49
POLB P06746 1/20 0.49
KIF18A Q8NI77 1/20 0.47
HPGD P15428 1/20 0.46
ALOX15 P16050 1/20 0.46
HSD17B10 Q99714 1/20 0.46
NAMPT P43490 1/20 0.45
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7871346 0.89 PTGS2 (0.56) ALDH1A1CYP3A4MAPK1PTGS2PTGS1
SCHEMBL10869745 0.89 ALDH1A1 (0.68) ALDH1A1CYP3A4MAPK1PTGS2PTGS1
SCHEMBL5161585 0.89 PTGS2 (0.54) ALDH1A1CYP3A4MAPK1PTGS2PTGS1
SCHEMBL7643603 0.85 PTGS2 (0.54) ALDH1A1CYP3A4MAPK1PTGS2PTGS1
SCHEMBL2034446 0.83 HSD11B1 (0.68) ALDH1A1CYP3A4MAPK1CNR2KDM4E
SCHEMBL10459473 0.83 ALDH1A1 (0.46) ALDH1A1CYP3A4MAPK1PTGS2PTGS1
SCHEMBL9793431 0.82 HTR6 (0.62) ALDH1A1KDM4EKMT2APOLBHSD17B10
SCHEMBL7199480 0.81 ALDH1A1 (0.62) ALDH1A1CYP3A4MAPK1CNR2KDM4E
SCHEMBL8058706 0.81 ALDH1A1 (0.47) ALDH1A1CYP3A4MAPK1PTGS2PTGS1
SCHEMBL3446333 0.80 CNR1 (0.58) ALDH1A1CYP3A4MAPK1CNR2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080293840-A1 POLYPHENYLENE-POLY(ARYL ETHER SULFONE) BLENDS, ARTICLES AND METHOD SOLVAY ADVANCED POLYMERS L.L.C. (US) 2008-11-27 US claimed
EP-1754743-B1 Flexible polymer element as toughening agent in prepregs CYTEC TECH CORP (US) 2020-05-13 EP disclosed
US-20200032086-A1 COMPOSITIONS CONTAINING HOLE CARRIER MATERIALS AND POLY(ARYL ETHER SULFONE)S, AND USES THEREOF SOLVAY USA INC. 2020-01-30 US disclosed
US-20170362451-A1 COMPOSITIONS CONTAINING HOLE CARRIER MATERIALS AND POLY(ARYL ETHER SULFONE)S, AND USES THEREOF SOLVAY USA INC. 2017-12-21 US disclosed
EP-3234018-A1 COMPOSITIONS CONTAINING HOLE CARRIER MATERIALS AND POLY(ARYL ETHER SULFONE)S, AND USES THEREOF Nissan Chemical Industries, Ltd. (JP) 2017-10-25 EP disclosed
WO-2016100321-A1 COMPOSITIONS CONTAINING HOLE CARRIER MATERIALS AND POLY(ARYL ETHER SULFONE)S, AND USES THEREOF SOLVAY USA, INC. (US) 2016-06-23 WO disclosed
US-8927662-B2 Binder of reactive polyarylethersulphone and epoxy resin CYTEC TECHNOLOGY CORP. (US) 2015-01-06 US disclosed
EP-1341850-B2 THERMALLY STABLE BINDER RESIN COMPOSITION AND METHOD FOR BINDING FIBRES CYTEC TECH CORP (US) 2013-08-14 EP disclosed
US-7750091-B2 Foam that is a blend of a polyphenylene with units derived from p-dichlorobenzophenone and m-dichlorobenzene and a polyphenyl ether sulfone with p,p'-biphenyl and diphenyl sulfone units; useful in numerous applications such as in the preparation of articles and of foams having reduced density SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2010-07-06 US disclosed
US-20090151860-A1 FLEXIBLE POLYMER ELEMENT FOR A CURABLE COMPOSITION CARTER JEFFREY THOMAS 2009-06-18 US disclosed
EP-0311349-B1 Polymer composition ICI PLC (GB) 1996-09-11 EP disclosed
US-5434224-A Fiber-reinforced structed having advantageous fracture toughness IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1995-07-18 US disclosed
EP-0278720-B1 Aromatic polymer VICTREX MFG LTD (GB) 1995-01-18 EP disclosed
US-5374694-A Thermosetting cyanato benzene-methano indene adduct or oligomer with thermoplastic resin containing ether or sulfide linked aryl sulfone groups ICI COMPOSITES INC. (US) 1994-12-20 US disclosed
US-5364914-A Moulding composition comprising a thermoset component and thermoplast component IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1994-11-15 US disclosed
US-5116933-A Crystalline IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1992-05-26 US disclosed
EP-0391581-A2 Composite structure IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-10-10 EP disclosed
EP-0365168-A2 Moulding composition comprising a thermoset component and thermoplast component IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-04-25 EP disclosed
EP-0311349-A2 Polymer composition IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1989-04-12 EP disclosed
EP-0010595-A1 Bis(4-hydroxyphenylthiophenyl)biphenyldisulphones and bis(4-hydroxyphenyl-sulphonylphenyl)-biphenyldisulphones, their preparation and their use Mobay Chemical Corporation (US) 1980-05-14 EP disclosed