Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.66 |
| ▸ | NPC1 | O15118 | 5/20 | 0.66 |
| ▸ | RAB9A | P51151 | 5/20 | 0.66 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.62 |
| ▸ | KCNK3 | O14649 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | RAF1 | P04049 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | BRAF | P15056 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14375922 | 0.88 | NPC1 (0.62) | KMT2ANPC1RAB9AKCNK3MAPT | |
| SCHEMBL11483074 | 0.84 | KMT2A (0.61) | KMT2ANPC1RAB9AFKBP5KCNK3 | |
| SCHEMBL28622654 | 0.82 | RAB9A (0.93) | KMT2ANPC1RAB9AFKBP5KCNK3 | |
| SCHEMBL4701359 | 0.80 | KMT2A (0.71) | KMT2ANPC1RAB9AFKBP5KCNK3 | |
| SCHEMBL6778190 | 0.80 | KMT2A (0.71) | KMT2ANPC1RAB9AFKBP5KCNK3 | |
| SCHEMBL10383130 | 0.79 | ALDH1A1 (0.50) | KMT2ANPC1RAB9AMAPTMEN1 | |
| SCHEMBL6054992 | 0.78 | NPC1 (0.78) | KMT2ANPC1RAB9AFKBP5KCNK3 | |
| SCHEMBL3241551 | 0.78 | KMT2A (0.69) | KMT2ANPC1RAB9AFKBP5KCNK3 | |
| SCHEMBL7748140 | 0.78 | NPC1 (0.73) | KMT2ANPC1RAB9AFKBP5KCNK3 | |
| SCHEMBL29744477 | 0.78 | KMT2A (0.69) | KMT2ANPC1RAB9AFKBP5KCNK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0254858-B1 | CHROMOGENIC 3,1-BENZOXAZINE | BAYER AG (DE) | 1990-10-31 | — | — | EP | disclosed |
| US-4831141-A | PRESSURE SENSITIVE RECORDING | BAYER AKTIENGESELLSCHAFT (DE) | 1989-05-16 | — | — | US | disclosed |
| EP-0254858-A2 | Chromogenic 3,1-benzoxazine | BAYER AG (DE) | 1988-02-03 | — | — | EP | disclosed |