SCHEMBL10355752

SCHEMBL10355752

C=C(C)C(=O)OCCOCCOC(COC(=O)C(=C)C)CC(=C)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.47
TSHR P16473 3/20 0.42
POLB P06746 1/20 0.32
APEX1 P27695 1/20 0.32
HTT P42858 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
TET2 Q6N021 3/20 0.31
TET3 O43151 1/20 0.31
TET1 Q8NFU7 1/20 0.31
GRIK1 P39086 1/20 0.30
GRIK2 Q13002 1/20 0.30
GRM1 Q13255 1/20 0.30
GRM2 Q14416 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4632373 0.91 THRB (0.55) THRBTSHRPOLBAPEX1HTT
SCHEMBL2407775 0.88 THRB (0.43) THRBTSHR
SCHEMBL6523772 0.83 TSHR (0.45) THRBTSHRPOLBAPEX1HTT
SCHEMBL11751848 0.81 THRB (0.45) THRBTSHR
Methacrylic Acid SCHEMBL1179050 0.80 THRB (0.49) THRBTSHR
SCHEMBL17075267 0.80 ALDH1A1 (0.56) THRBTSHR
SCHEMBL248094 0.79 TSHR (0.50) THRBTSHRPOLBAPEX1HTT
SCHEMBL996774 0.79 THRB (0.59) THRBTSHRPOLBAPEX1HTT
SCHEMBL7545167 0.78 THRB (0.52) THRBTSHRPOLBAPEX1HTT
Methacrylic Acid SCHEMBL1561904 0.78 TSHR (0.49) THRBTSHRPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0206362-B1 ADHESIVE COATING MATERIAL TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1990-10-17 EP disclosed
EP-0206362-A1 Adhesive coating material TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1986-12-30 EP disclosed
US-4535102-A CARBOXYLIC MONOMER WITH UNSATURATED ESTER OR OTHER VINYL COMPOUND AND ORGANIC TITANATE AND INITIATOR TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1985-08-13 US disclosed
EP-0103420-A2 Adhesive coating material TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1984-03-21 EP disclosed