SCHEMBL2407775

SCHEMBL2407775

C=C(C)C(=O)OCCOCCOCCOC(COC(=O)NCC)CC(=C)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.43
TSHR P16473 3/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
CHRNB2 P17787 1/20 0.31
CHRNB4 P30926 1/20 0.31
CHRNA3 P32297 1/20 0.31
CHRNA4 P43681 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10355752 0.88 THRB (0.47) THRBTSHR
SCHEMBL4632373 0.84 THRB (0.55) THRBTSHR
SCHEMBL20089019 0.78 THRB (0.62) THRBTSHRCHRNB2CHRNB4CHRNA3
Methacrylic Acid SCHEMBL1179050 0.75 THRB (0.49) THRBTSHR
SCHEMBL6523772 0.75 TSHR (0.45) THRBTSHR
SCHEMBL890339 0.74 THRB (0.58) THRBTSHRCHRNB2CHRNB4CHRNA3
SCHEMBL11751848 0.73 THRB (0.45) THRBTSHR
SCHEMBL7545167 0.73 THRB (0.52) THRBTSHR
SCHEMBL996774 0.71 THRB (0.59) THRBTSHR
SCHEMBL13955819 0.70 THRB (0.51) THRBTSHRSMN1; SMN2CHRNB2CHRNB4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020237363-A1 COMPOSITE PARTICLES COMPRISING A HYDROPHOBIC DYE AND AN AMPHIPHILIC BLOCK COPOLYMER AND USE THEREOF IN OPTICAL APPLICATIONS COLOURSMITH LABS INC. (CA) 2020-12-03 WO disclosed
EP-1789821-B1 SILICONE HYDROGEL CONTACT LENSES COOPERVISION INT HOLDING CO LP (BB) 2019-04-10 EP disclosed
US-9322958-B2 Silicone hydrogel contact lenses COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) 2016-04-26 US disclosed
US-20150219795-A9 Silicone Hydrogel Contact Lenses COOPERVISION INTERNATIONAL LIMITED (GB) 2015-08-06 US disclosed
US-20140200286-A1 Silicone Hydrogel Contact Lenses COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) 2014-07-17 US disclosed
US-8637621-B2 Long-wearable soft contact lens COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) 2014-01-28 US disclosed
US-8614261-B2 Silicone hydrogel contact lens COOPERVISION INTERNATIONAL HOLDING COMPANY LP (BB) 2013-12-24 US disclosed
EP-1243960-B2 SOFT CONTACT LENS CAPABLE OF BEING WORN FOR A LONG PERIOD COOPERVISION INT HOLDING CO LP (BB) 2013-10-16 EP disclosed
US-8367746-B2 Silicone hydrogel contact lens COOPERVISION INTERNATIONAL HOLDING COMPANY (BB) 2013-02-05 US disclosed
US-20120252925-A1 Silicone Hydrogel Contact Lens COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) 2012-10-04 US disclosed
US-20110211158-A1 Long-Wearable Soft Contact Lens COOPERVISION INTERNATIONAL LIMITED (GB) 2011-09-01 US disclosed
EP-1789821-A2 SILICONE HYDROGEL CONTACT LENSES ASAHIKASEI AIME CO., Ltd. (JP) 2007-05-30 EP disclosed
US-20070066706-A1 Silicone hydrogel contact lens COOPERVISION, INC. (US) 2007-03-22 US disclosed
US-20060211789-A1 Long-wearable soft contact lens ASAHIKASEI AIME CO., LTD. (JP) 2006-09-21 US disclosed
US-20060063852-A1 Silicone hydrogel contact lens ASAHIKASEI AIME CO. LTD. (JP) 2006-03-23 US disclosed
WO-2006026474-A2 SILICONE HYDROGEL CONTACT LENSES ASAHIKASEI AIME CO. LTD. (JP) 2006-03-09 WO disclosed
US-20040192872-A1 Long-wearable soft contact lens ASAHIKASEI AIME CO., LTD (JP) 2004-09-30 US disclosed
EP-1243960-A1 SOFT CONTACT LENS CAPABLE OF BEING WORN FOR A LONG PERIOD ASAHIKASEI AIME CO., Ltd. (JP) 2002-09-25 EP disclosed
US-20020016383-A1 Long wearable soft contact lens COOPERVISION INTERNATIONAL LIMITED (GB) 2002-02-07 US disclosed