Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11656908 | 0.85 | ALDH1A1 (0.40) | ALDH1A1THRBTSHRTP53 | |
| SCHEMBL2789568 | 0.83 | ALDH1A1 (0.64) | ALDH1A1TSHRCYP3A4TP53CYP2D6 | |
| SCHEMBL10355752 | 0.80 | THRB (0.47) | THRBTSHR | |
| SCHEMBL8094497 | 0.79 | ALDH1A1 (0.89) | ALDH1A1THRBTSHRCYP3A4TP53 | |
| SCHEMBL1683307 | 0.78 | ALDH1A1 (0.70) | ALDH1A1THRBTSHRCYP3A4TP53 | |
| Ethylene SCHEMBL21750074 | 0.78 | ALDH1A1 (0.86) | ALDH1A1THRBTSHRCYP3A4TP53 | |
| SCHEMBL11751848 | 0.77 | THRB (0.45) | THRBTSHR | |
| SCHEMBL6523772 | 0.77 | TSHR (0.45) | ALDH1A1THRBTSHR | |
| SCHEMBL4648009 | 0.77 | ALDH1A1 (0.64) | ALDH1A1THRBTSHRCYP3A4TP53 | |
| SCHEMBL673217 | 0.76 | ALDH1A1 (0.72) | ALDH1A1THRBTSHRCYP3A4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111234054-A | Double-effect initiator and photopolymerization and thermal polymerization method | 山东非金属材料研究所 | 2020-06-05 | — | — | CN | claimed |
| US-10246540-B2 | Rapid azeotropic photo-copolymerization of styrene and methacrylate derivatives and uses thereof | ADA FOUNDATION (US) | 2019-04-02 | — | — | US | claimed |
| US-10966909-B2 | Resin composites for use in dental preventive and restorative applications | ADA FOUNDATION (US) | 2021-04-06 | — | — | US | disclosed |
| US-20200297587-A1 | RESIN COMPOSITES FOR USE IN DENTAL PREVENTIVE AND RESTORATIVE APPLICATIONS | ADA FOUNDATION (US) | 2020-09-24 | — | — | US | disclosed |
| US-10675224-B2 | Enzymatically and hydrolytically stable dental preventive and restorative systems | ADA FOUNDATION (US) | 2020-06-09 | — | — | US | disclosed |
| US-20190209438-A1 | ENZYMATICALLY AND HYDROLYTICALLY STABLE DENTAL PREVENTIVE AND RESTORATIVE SYSTEMS | ADA FOUNDATION (US) | 2019-07-11 | — | — | US | disclosed |
| US-10231906-B2 | Enzymatically and hydrolytically stable dental preventive and restorative systems | ADA FOUNDATION (US) | 2019-03-19 | — | — | US | disclosed |
| EP-3270870-A1 | ENZYMATICALLY AND HYDROLYTICALLY STABLE RESINS, RESIN MONOMERS, AND RESIN COMPOSITES FOR USE IN DENTAL APPLICATIONS | ADA FOUNDATION (US) | 2018-01-24 | — | — | EP | disclosed |
| US-20170049666-A1 | ENZYMATICALLY AND HYDROLYTICALLY STABLE DENTAL PREVENTIVE AND RESTORATIVE SYSTEMS | ADA FOUND (US) | 2017-02-23 | — | — | US | disclosed |
| US-9572753-B2 | Enzymatically and hydrolytically stable resins, resin monomers, and resin composites for use in dental preventive and restorative applications | ADA FOUNDATION (US) | 2017-02-21 | — | — | US | disclosed |
| WO-2016160299-A1 | ENZYMATICALLY AND HYDROLYTICALLY STABLE RESINS, RESIN MONOMERS, AND RESIN COMPOSITES FOR USE IN DENTAL APPLICATIONS | ADA FOUNDATION (US) | 2016-10-06 | — | — | WO | disclosed |
| US-20150257986-A1 | ENZYMATICALLY AND HYDROLYTICALLY STABLE RESINS, RESIN MONOMERS, AND RESIN COMPOSITES FOR USE IN DENTAL PREVENTIVE AND RESTORATIVE APPLICATIONS | ADA FOUNDATION | 2015-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190209438-A1 | ENZYMATICALLY AND HYDROLYTICALLY STABLE DENTAL PREVENTIVE AND RESTORATIVE SYSTEMS | GGH, DNPH1, BCHE | ALDH1A1 321/4885THRB 3395/4885TSHR 4797/4885 |
| US-10675224-B2 | Enzymatically and hydrolytically stable dental preventive and restorative systems | GGH, DNPH1, BCHE | ALDH1A1 321/4885THRB 3395/4885TSHR 4797/4885 |
| US-10966909-B2 | Resin composites for use in dental preventive and restorative applications | SUV39H2, CBX3, SUV39H1 | ALDH1A1 1332/4885THRB 2106/4885TSHR 4233/4885 |
| US-20170049666-A1 | ENZYMATICALLY AND HYDROLYTICALLY STABLE DENTAL PREVENTIVE AND RESTORATIVE SYSTEMS | GGH, DNPH1, BCHE | ALDH1A1 321/4885THRB 3395/4885TSHR 4797/4885 |
| US-20200297587-A1 | RESIN COMPOSITES FOR USE IN DENTAL PREVENTIVE AND RESTORATIVE APPLICATIONS | SUV39H2, CBX3, SUV39H1 | ALDH1A1 1332/4885THRB 2106/4885TSHR 4233/4885 |
| US-20150257986-A1 | ENZYMATICALLY AND HYDROLYTICALLY STABLE RESINS, RESIN MONOMERS, AND RESIN COMPOSITES FOR USE IN DENTAL PREVENTIVE AND RESTORATIVE APPLICATIONS | ESD, JMJD6, DNPH1 | ALDH1A1 377/4885THRB 3648/4885TSHR 4610/4885 |
| US-10231906-B2 | Enzymatically and hydrolytically stable dental preventive and restorative systems | GGH, DNPH1, BCHE | ALDH1A1 321/4885THRB 3395/4885TSHR 4797/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.