SCHEMBL10357151

SCHEMBL10357151

CC(C)[C@H](N)C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ NOD1 Q9Y239 3/20 0.41
▸ NPY4R P50391 11/20 0.39
▸ NPY5R Q15761 8/20 0.39
▸ NPY1R P25929 7/20 0.39
▸ NPY2R P49146 5/20 0.39
▸ C3AR1 Q16581 1/20 0.38
▸ FNTA P49354 2/20 0.38
▸ FNTB P49356 2/20 0.38
▸ PGGT1B P53609 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10357149 1.00 NOD1 (0.41) NOD1NPY4RNPY5RNPY1RNPY2R
SCHEMBL30197694 0.92 NOD1 (0.40) NOD1NPY4RNPY5RNPY1RNPY2R
SCHEMBL29635279 0.90 NPY4R (0.47) NPY4RNPY5RNPY1RNPY2R
SCHEMBL30929896 0.90 NOD1 (0.47) NOD1NPY4RNPY5RNPY1RNPY2R
SCHEMBL29678580 0.90 TERT (0.42) NOD1NPY4RNPY5RNPY1RNPY2R
SCHEMBL29358945 0.89 NPY4R (0.42) NOD1NPY4RNPY5RNPY1RNPY2R
SCHEMBL29358971 0.89 NPY4R (0.42) NOD1NPY4RNPY5RNPY1RNPY2R
SCHEMBL7242707 0.89 NPY4R (0.42) NOD1NPY4RNPY5RNPY1RNPY2R
SCHEMBL7098551 0.89 NPY4R (0.42) NOD1NPY4RNPY5RNPY1RNPY2R
SCHEMBL29357342 0.89 NPY4R (0.42) NOD1NPY4RNPY5RNPY1RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0167152-B1 PROTEASE ADSORBENT AND PROCESS FOR PURIFYING TPA UTILIZING THE SAME NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1990-11-14 — — EP claimed
US-20260146247-A1 Compositions and Methods for Targeted Delivery of CRISPR-CAS Effector Polypeptides and Transgenes THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-05-28 — — US disclosed
US-12624063-B2 Compositions and methods for modification of target molecules THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-05-12 — — US disclosed
US-20260109753-A1 Syntac Polypeptides and Uses Thereof ALBERT EINSTEIN COLLEGE MEDICINE (US) 2026-04-23 — — US disclosed
US-20260070959-A1 T-Cell Modulatory Chimeric Molecules and Methods of Use Thereof CUE BIOPHARMA INC (US) 2026-03-12 — — US disclosed
US-12565647-B2 Compositions and methods for targeted delivery of CRISPR-Cas effector polypeptides and transgenes THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-03-03 — — US disclosed
US-12534722-B2 Euglobulin-based method for determining the biological activity of defibrotide GENTIUM S.R.L. (IT) 2026-01-27 — — US disclosed
US-12529052-B2 Euglobulin-based method for determining the biological activity of defibrotide GENTIUM S.R.L. (IT) 2026-01-20 — — US disclosed
US-20260015381-A1 COMPOSITIONS AND METHODS FOR MODIFICATION OF TARGET MOLECULES UNIV CALIFORNIA (US) 2026-01-15 — — US disclosed
US-20260008996-A1 Compositions and Methods for Modification of Cells UNIV CALIFORNIA (US) 2026-01-08 — — US disclosed
CN-114728172-A Notch receptors with minimal linkers 加利福尼亚大学董事会 2022-07-08 — — CN disclosed
CN-114728174-A Receptors with heterologous transmembrane domains 加利福尼亚大学董事会 2022-07-08 — — CN disclosed
CN-114728173-A Novel receptors with heterologous stop transfer sequences for ligand-dependent transcriptional regulation 加利福尼亚大学董事会 2022-07-08 — — CN disclosed
US-11358995-B2 Compositions and methods of use for treating metabolic disorders NGM BIOPHARMACEUTICALS, INC. (US) 2022-06-14 — — US disclosed
CN-114599674-A T cell modulating chimeric molecules and methods of use thereof 库尔生物制药有限公司 2022-06-07 — — CN disclosed
US-20220153779-A1 COMPOSITIONS AND METHODS FOR MODIFICATION OF TARGET MOLECULES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2022-05-19 — — US disclosed
CN-106687128-B Compositions and methods for treating metabolic disorders NGM生物制药有限公司 2022-05-10 — — CN disclosed
US-20220133797-A1 NOTCH RECEPTORS WITH HINGE DOMAIN THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2022-05-05 — — US disclosed
CN-106573966-B Compositions and methods for treating metabolic abnormalities NGM生物制药有限公司 2022-03-01 — — CN disclosed
US-11236328-B2 Euglobulin-based method for determining the biological activity of defibrotide GENTIUM S.R.L. (IT) 2022-02-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260070959-A1 T-Cell Modulatory Chimeric Molecules and Methods of Use Thereof ICOS, ICOSLG, CD274 NOD1 1611/4885NPY4R 899/4885NPY5R 2356/4885
US-20260109753-A1 Syntac Polypeptides and Uses Thereof ICOS, CD40LG, CD40 NOD1 466/4885NPY4R 464/4885NPY5R 501/4885
US-12624063-B2 Compositions and methods for modification of target molecules TYR, TH, COMT NOD1 2801/4885NPY4R 735/4885NPY5R 1220/4885
US-20260015381-A1 COMPOSITIONS AND METHODS FOR MODIFICATION OF TARGET MOLECULES TH, COMT, TYR NOD1 1360/4885NPY4R 2246/4885NPY5R 2336/4885
US-20260008996-A1 Compositions and Methods for Modification of Cells CD2, CD47, EPCAM NOD1 3143/4885NPY4R 2604/4885NPY5R 2189/4885
US-12529052-B2 Euglobulin-based method for determining the biological activity of defibrotide FGB, PLG, F2 NOD1 1329/4885NPY4R 3918/4885NPY5R 3688/4885
US-12565647-B2 Compositions and methods for targeted delivery of CRISPR-Cas effector polypeptides and transgenes CD4, PBK, HAVCR2 NOD1 2841/4885NPY4R 2784/4885NPY5R 3078/4885
US-20260146247-A1 Compositions and Methods for Targeted Delivery of CRISPR-CAS Effector Polypeptides and Transgenes LNPEP, PRNP, CPSF1 NOD1 4080/4885NPY4R 3628/4885NPY5R 4211/4885
US-12534722-B2 Euglobulin-based method for determining the biological activity of defibrotide FGB, PLG, F2 NOD1 1460/4885NPY4R 3916/4885NPY5R 3777/4885
US-20220153779-A1 COMPOSITIONS AND METHODS FOR MODIFICATION OF TARGET MOLECULES COMT, TH, AOX1 NOD1 2919/4885NPY4R 4682/4885NPY5R 4512/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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