Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.63 |
| ▸ | POLB | P06746 | 3/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 6/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | RECQL | P46063 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | STAT3 | P40763 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10358385 | 0.84 | SMN1; SMN2 (0.67) | MAPTALDH1A1SMN1; SMN2POLBHPGD | |
| SCHEMBL10358371 | 0.83 | SMN1; SMN2 (0.66) | MAPTALDH1A1SMN1; SMN2POLBHPGD | |
| SCHEMBL4984046 | 0.81 | MAPT (0.73) | MAPTALDH1A1SMN1; SMN2POLBHPGD | |
| SCHEMBL9811103 | 0.79 | POLB (0.63) | MAPTALDH1A1SMN1; SMN2POLBHPGD | |
| SCHEMBL10358374 | 0.78 | ALOX5 (0.60) | MAPTALDH1A1SMN1; SMN2POLBHPGD | |
| SCHEMBL144880 | 0.78 | SMN1; SMN2 (1.00) | MAPTALDH1A1SMN1; SMN2POLBHPGD | |
| SCHEMBL29367809 | 0.78 | SMN1; SMN2 (1.00) | MAPTALDH1A1SMN1; SMN2POLBHPGD | |
| SCHEMBL10643875 | 0.77 | SMN1; SMN2 (0.64) | MAPTALDH1A1SMN1; SMN2POLBHPGD | |
| SCHEMBL13629729 | 0.77 | SMN1; SMN2 (0.76) | MAPTALDH1A1SMN1; SMN2POLBHPGD | |
| SCHEMBL29229036 | 0.77 | SMN1; SMN2 (0.97) | MAPTALDH1A1SMN1; SMN2POLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161222-B1 | HETEROCYCLIC MERCAPTOCARBOXYLIC-ACID AMIDES, IMIDES AND NITRILES AS CORROSION INHIBITING AGENTS | CIBA-GEIGY AG (CH) | 1990-10-10 | — | — | EP | disclosed |
| US-4719036-A | PAINTS; METAL WORKING | CIBA-GEIGY CORPORATION (US) | 1988-01-12 | — | — | US | disclosed |
| EP-0161222-A2 | Heterocyclic mercaptocarboxylic-acid amides, imides and nitriles as corrosion inhibiting agents | CIBA-GEIGY AG (CH) | 1985-11-13 | — | — | EP | disclosed |