Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.38 |
| ▸ | TDP2 | O95551 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10358336 | 0.82 | SMN1; SMN2 (0.41) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL10358301 | 0.82 | DYRK1A (0.39) | NPC1RAB9ANPSR1ALDH1A1TP53 | |
| SCHEMBL10758155 | 0.75 | MEN1 (0.43) | MEN1KMT2ANPC1RAB9ANPSR1 | |
| SCHEMBL10358744 | 0.74 | ALDH1A1 (0.56) | MEN1KMT2ANPC1RAB9ANPSR1 | |
| SCHEMBL9195319 | 0.71 | KMT2A (0.56) | MEN1KMT2AADAMTS5NPSR1ALDH1A1 | |
| SCHEMBL10359349 | 0.71 | ALDH1A1 (0.53) | MEN1KMT2ANPC1RAB9ANPSR1 | |
| SCHEMBL10644848 | 0.70 | NPY5R (0.45) | NPC1RAB9AADAMTS5NPSR1ALDH1A1 | |
| SCHEMBL10640796 | 0.69 | ADAMTS5 (0.40) | MEN1KMT2ANPC1RAB9AADAMTS5 | |
| SCHEMBL24191465 | 0.69 | KCNH2 (0.59) | MEN1KMT2ANPSR1ALDH1A1TP53 | |
| SCHEMBL11245696 | 0.69 | DDB1 (0.49) | KMT2ANPC1ALDH1A1TP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161222-B1 | HETEROCYCLIC MERCAPTOCARBOXYLIC-ACID AMIDES, IMIDES AND NITRILES AS CORROSION INHIBITING AGENTS | CIBA-GEIGY AG (CH) | 1990-10-10 | — | — | EP | disclosed |
| US-4719036-A | PAINTS; METAL WORKING | CIBA-GEIGY CORPORATION (US) | 1988-01-12 | — | — | US | disclosed |
| EP-0161222-A2 | Heterocyclic mercaptocarboxylic-acid amides, imides and nitriles as corrosion inhibiting agents | CIBA-GEIGY AG (CH) | 1985-11-13 | — | — | EP | disclosed |