Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPH1 | P17752 | 7/20 | 0.48 |
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.46 |
| ▸ | ALPI | P09923 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | XIAP | P98170 | 1/20 | 0.46 |
| ▸ | TYR | P14679 | 5/20 | 0.42 |
| ▸ | GRB2 | P62993 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10359243 | 0.84 | TPH1 (0.39) | TPH1SLC7A5PTGS1ALPIPKM | |
| SCHEMBL8844863 | 0.79 | SLC7A5 (0.57) | TPH1SLC7A5PTGS1ALPIPKM | |
| SCHEMBL11010339 | 0.78 | LNPEP (0.41) | HSD17B10ALDH1A1LMNA | |
| SCHEMBL11020769 | 0.78 | LNPEP (0.41) | HSD17B10ALDH1A1LMNA | |
| SCHEMBL9618798 | 0.77 | NOS3 (0.42) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL10870900 | 0.77 | NOS3 (0.42) | SLC7A5PTGS1ALPIPKMXIAP | |
| Phenylalanine Methyl Ester SCHEMBL14988983 | 0.73 | SLC7A5 (0.47) | SLC7A5PTGS1ALPIPKMXIAP | |
| Phenylalanine SCHEMBL7165251 | 0.73 | SLC7A5 (0.56) | TPH1SLC7A5PTGS1ALPIPKM | |
| SCHEMBL9515152 | 0.73 | ALPI (0.45) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL2310526 | 0.72 | SLC7A5 (0.83) | TPH1SLC7A5PTGS1ALPIPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0200311-B1 | PREPARATION PROCESS OF ALPHA-L-ASPARTYL-L-PHENYLALANINE METHYL ESTER OR HYDROCHLORIDE THEREOF | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-10-10 | — | — | EP | disclosed |