Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPH1 | P17752 | 1/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 8/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11020769 | 0.88 | LNPEP (0.41) | L3MBTL1 | |
| SCHEMBL11010339 | 0.88 | LNPEP (0.41) | L3MBTL1 | |
| SCHEMBL10359245 | 0.84 | TPH1 (0.48) | TPH1SLC7A5MEN1KMT2AALPI | |
| SCHEMBL8844863 | 0.79 | SLC7A5 (0.57) | TPH1SLC7A5PTPN1MEN1KMT2A | |
| SCHEMBL27849759 | 0.77 | ALPI (0.35) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL10870881 | 0.77 | ALPI (0.35) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL11235526 | 0.76 | TAAR1 (0.49) | — | |
| SCHEMBL3799467 | 0.75 | FOLH1 (0.54) | SLC7A5CA2CA1MEN1KMT2A | |
| SCHEMBL4611286 | 0.75 | FOLH1 (0.54) | SLC7A5CA2CA1MEN1KMT2A | |
| SCHEMBL2703294 | 0.75 | FOLH1 (0.54) | SLC7A5CA2CA1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0200311-B1 | PREPARATION PROCESS OF ALPHA-L-ASPARTYL-L-PHENYLALANINE METHYL ESTER OR HYDROCHLORIDE THEREOF | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-10-10 | — | — | EP | disclosed |