Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 6/20 | 0.41 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9292329 | 0.87 | CYP3A4 (0.51) | SMN1; SMN2PKMCYP3A4NPSR1CYP2C19 | |
| SCHEMBL9879546 | 0.83 | SMN1; SMN2 (0.52) | SMN1; SMN2PKMCYP3A4NPSR1CYP2C19 | |
| SCHEMBL4941845 | 0.83 | SMN1; SMN2 (0.48) | SMN1; SMN2PKMCYP3A4NPSR1CYP2C19 | |
| SCHEMBL27579705 | 0.83 | PKM (0.48) | SMN1; SMN2PKMCYP3A4NPSR1CYP2C19 | |
| SCHEMBL28110882 | 0.83 | CYP2C19 (0.50) | SMN1; SMN2PKMCYP3A4NPSR1CYP2C19 | |
| SCHEMBL5323999 | 0.80 | GABBR2 (0.57) | SMN1; SMN2PKMCYP3A4NPSR1CYP2C19 | |
| SCHEMBL9857372 | 0.79 | CASP1 (0.48) | SMN1; SMN2PKMCYP3A4NPSR1CYP2C19 | |
| SCHEMBL27815512 | 0.79 | LMNA (0.39) | SMN1; SMN2CYP3A4CYP2C19ALDH1A1BCAT2 | |
| SCHEMBL295741 | 0.78 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1TSHRLMNAMAPT | |
| SCHEMBL7056947 | 0.78 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1TSHRLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8377856-B2 | Extended drain diesel lubricant formulations | AFTON CHEMICAL CORPORATION (US) | 2013-02-19 | — | — | US | claimed |
| US-20110003722-A1 | EXTENDED DRAIN DIESEL LUBRICANT FORMULATIONS | AFTON CHEMICAL CORPORATION (US) | 2011-01-06 | — | — | US | claimed |
| US-20100292112-A1 | EXTENDED DRAIN DIESEL LUBRICANT FORMULATIONS | AFTON CHEMICAL CORPORATION (US) | 2010-11-18 | — | — | US | claimed |
| US-20100292112-A1 | EXTENDED DRAIN DIESEL LUBRICANT FORMULATIONS | AFTON CHEMICAL CORPORATION (US) | 2010-11-18 | — | — | US | disclosed |