Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 13/20 | 0.48 |
| ▸ | DRD2 | P14416 | 4/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | MOGAT2 | Q3SYC2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10360426 | 0.88 | LTA4H (0.68) | LTA4HHRH3DRD2SLC6A4ADRA1D | |
| SCHEMBL10360469 | 0.73 | DRD2 (0.56) | DRD2MOGAT2 | |
| SCHEMBL7859721 | 0.71 | LTA4H (0.88) | LTA4HHRH3 | |
| SCHEMBL10361497 | 0.71 | KDM4E (0.49) | LTA4HHRH3DRD2 | |
| SCHEMBL9124515 | 0.70 | LTA4H (0.73) | LTA4HHRH3 | |
| SCHEMBL18088625 | 0.70 | ALDH1A1 (0.50) | — | |
| SCHEMBL10360467 | 0.70 | HRH3 (0.50) | LTA4HHRH3 | |
| SCHEMBL10281943 | 0.70 | LTA4H (0.53) | LTA4HHRH3 | |
| Water SCHEMBL9125025 | 0.69 | LTA4H (0.71) | LTA4HHRH3 | |
| SCHEMBL9807583 | 0.69 | LTA4H (0.56) | LTA4HHRH3DRD2SLC6A4ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0284384-B1 | ANTI-ARRHYTHMIC AGENTS | Pfizer Limited (GB) | 1990-11-28 | — | — | EP | disclosed |
| US-4891372-A | Antiarrhythmic agents, compositions and method of use thereas | PFIZER INC. (US) | 1990-01-02 | — | — | US | disclosed |
| EP-0284384-A1 | Anti-arrhythmic agents | Pfizer Limited (GB) | 1988-09-28 | — | — | EP | disclosed |