Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.56 |
| ▸ | DRD3 | P35462 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | HTR2C | P28335 | 1/20 | 0.56 |
| ▸ | HTR6 | P50406 | 1/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.53 |
| ▸ | MOGAT2 | Q3SYC2 | 2/20 | 0.51 |
| ▸ | MLNR | O43193 | 8/20 | 0.48 |
| ▸ | GHSR | Q92847 | 4/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9625696 | 0.82 | LTA4H (0.58) | CYP1A2CYP3A4KDM4EALDH1A1LMNA | |
| SCHEMBL9625327 | 0.82 | LTA4H (0.58) | CYP1A2CYP3A4KDM4EALDH1A1LMNA | |
| SCHEMBL10360426 | 0.81 | LTA4H (0.68) | DRD2DRD3ABCB1KCNH2 | |
| SCHEMBL7854117 | 0.81 | LTA4H (0.56) | KCNH2KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL9592073 | 0.80 | KCNH2 (0.52) | DRD2DRD3KCNH2KDM4EALDH1A1 | |
| SCHEMBL10359567 | 0.78 | LMNA (0.55) | DRD2HTR2AHTR2CKCNH2KDM4E | |
| SCHEMBL7435504 | 0.78 | RAB9A (0.51) | DRD2DRD3KCNH2SMN1; SMN2 | |
| SCHEMBL10359884 | 0.78 | GAA (0.63) | DRD2DRD3CYP2C19CYP2D6HTR2A | |
| Hydrochloric Acid SCHEMBL10398018 | 0.77 | OPRM1 (0.56) | DRD2DRD3CYP1A2CYP3A4CYP2C9 | |
| Hydrochloric Acid SCHEMBL10359568 | 0.77 | LMNA (0.54) | DRD2HTR2AHTR2CKCNH2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4891372-A | Antiarrhythmic agents, compositions and method of use thereas | PFIZER INC. (US) | 1990-01-02 | — | — | US | claimed |
| EP-0284384-B1 | ANTI-ARRHYTHMIC AGENTS | Pfizer Limited (GB) | 1990-11-28 | — | — | EP | disclosed |
| US-4891372-A | Antiarrhythmic agents, compositions and method of use thereas | PFIZER INC. (US) | 1990-01-02 | — | — | US | disclosed |
| EP-0284384-A1 | Anti-arrhythmic agents | Pfizer Limited (GB) | 1988-09-28 | — | — | EP | disclosed |