Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28571180 | 0.86 | MAOA (0.55) | DRD2KCNH2POLBMAOAPDK2 | |
| SCHEMBL819087 | 0.86 | KCNH2 (0.46) | DRD2KCNH2TRPA1PDK2HTR2B | |
| SCHEMBL17954603 | 0.85 | DRD2 (0.46) | DRD2KCNH2TRPA1PDK2HTR2B | |
| Fluorene SCHEMBL29055454 | 0.84 | MAOA (0.48) | KCNH2MAOATRPA1ESR2DRD3 | |
| SCHEMBL11677346 | 0.81 | TRPA1 (0.42) | DRD2KCNH2MAOATRPA1PDK2 | |
| SCHEMBL17954602 | 0.81 | TRPA1 (0.42) | DRD2KCNH2MAOATRPA1PDK2 | |
| SCHEMBL2120189 | 0.81 | MAOA (0.47) | DRD2KCNH2POLBMAOAHTR2B | |
| SCHEMBL17954606 | 0.81 | TRPA1 (0.41) | DRD2KCNH2MAOATRPA1PDK2 | |
| SCHEMBL17954612 | 0.80 | SQOR (0.40) | KCNH2POLBMAOATRPA1PDK2 | |
| SCHEMBL23862771 | 0.80 | KCNH2 (0.41) | DRD2KCNH2PDK2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102046598-B | Novel donor-acceptor fluorene scaffolds: a process and uses thereof | COUNCIL SCIENT IND RES | 2015-02-04 | — | — | CN | claimed |
| CN-102046598-A | Novel donor-acceptor fluorene scaffolds : a process and uses thereof | COUNCIL SCIENT IND RES | 2011-05-04 | — | — | CN | claimed |
| US-20160218300-A1 | Organic Electroluminescent Materials and Devices | UNIVERSAL DISPLAY CORPORATION | 2016-07-28 | — | — | US | disclosed |
| US-20160218300-A1 | Organic Electroluminescent Materials and Devices | UNIVERSAL DISPLAY CORPORATION | 2016-07-28 | — | — | US | disclosed |
| CN-102046598-B | Novel donor-acceptor fluorene scaffolds: a process and uses thereof | COUNCIL SCIENT IND RES | 2015-02-04 | — | — | CN | disclosed |
| US-8008507-B2 | Fluorescent diketopyrrolopyrroles | BASF SE Ludwigshafen (DE) | 2011-08-30 | — | — | US | disclosed |
| CN-102046598-A | Novel donor-acceptor fluorene scaffolds : a process and uses thereof | COUNCIL SCIENT IND RES | 2011-05-04 | — | — | CN | disclosed |
| EP-2276733-A2 | NOVEL DONOR-ACCEPTOR FLUORENE SCAFFOLDS: A PROCESS AND USES THEREOF | Council Of Scientific & Industrial Research (IN) | 2011-01-26 | — | — | EP | disclosed |
| EP-2215092-A1 | SUBSTITUTED PIPERIDINO-DIHYDROTHIENOPYRIMIDINES | Boehringer Ingelheim International GmbH (DE) | 2010-08-11 | — | — | EP | disclosed |
| WO-2009050248-A1 | SUBSTITUTED PIPERIDINO-DIHYDROTHIENOPYRIMIDINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-04-23 | — | — | WO | disclosed |
| EP-1817392-B1 | FLUORESCENT DIKETOPYRROLOPYRROLES | CIBA HOLDING INC (CH) | 2009-01-07 | — | — | EP | disclosed |
| US-20080217581-A1 | Inks, colorants, pigmented plastics for coatings, non-impact-printing material, color filters, cosmetics, polymeric ink particles, toners, fluorescent tracers; high in the efficiency of electrical energy utilisation and high in luminance | CIBA CORPORATION | 2008-09-11 | — | — | US | disclosed |
| EP-1817392-A1 | FLUORESCENT DIKETOPYRROLOPYRROLES | Ciba Specialty Chemicals Holding Inc. (CH) | 2007-08-15 | — | — | EP | disclosed |
| WO-2006061343-A1 | FLUORESCENT DIKETOPYRROLOPYRROLES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2006-06-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080217581-A1 | Inks, colorants, pigmented plastics for coatings, non-impact-printing material, color filters, cosmetics, polymeric ink particles, toners, fluorescent tracers; high in the efficiency of electrical energy utilisation and high in luminance | TYR, MC1R, IK | DRD2 1661/4885KCNH2 245/4885POLB 3563/4885 |
| US-20160218300-A1 | Organic Electroluminescent Materials and Devices | OCIAD2, OCIAD1, OSBP | DRD2 522/4885KCNH2 816/4885POLB 2757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.