Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.49 |
| ▸ | TGM2 | P21980 | 11/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | ITK | Q08881 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10816283 | 0.84 | TGM2 (0.47) | NCEH1TGM2ALDH1A1KDM4EHPGD | |
| SCHEMBL10364143 | 0.82 | NCEH1 (0.53) | NCEH1TGM2ALDH1A1HPGDMAPT | |
| SCHEMBL10363163 | 0.81 | SLC6A4 (0.58) | TGM2ALDH1A1KDM4EHPGDSLC6A4 | |
| SCHEMBL10362461 | 0.81 | L3MBTL1 (0.58) | TGM2ALDH1A1KDM4EHPGDSLC6A4 | |
| SCHEMBL10804531 | 0.81 | TGM2 (0.52) | TGM2ALDH1A1KDM4EHPGDSLC6A4 | |
| SCHEMBL11021590 | 0.80 | SLC6A4 (0.57) | TGM2ALDH1A1KDM4EHPGDSLC6A4 | |
| SCHEMBL10805912 | 0.80 | ALDH1A1 (0.42) | TGM2ALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL10363273 | 0.79 | RAB9A (0.56) | TGM2ALDH1A1KDM4EMAPTMEN1 | |
| SCHEMBL10804128 | 0.79 | TGM2 (0.46) | NCEH1TGM2ALDH1A1KDM4EHPGD | |
| SCHEMBL10364770 | 0.79 | TGM2 (0.43) | TGM2ALDH1A1KDM4EHPGDSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0155177-B1 | UNSATURATED CYCLIC AMIDO-SUBSTITUTED ETHER COMPOUNDS AND PREPARATION PROCESS THEREOF | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-10-31 | — | — | EP | disclosed |
| US-4649219-A | CROSSLINKERS, ADHESIVES, PAINTS | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1987-03-10 | — | — | US | disclosed |
| EP-0155177-A2 | Unsaturated cyclic amido-substituted ether compounds and preparation process thereof | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1985-09-18 | — | — | EP | disclosed |