Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.52 |
| ▸ | BPTF | Q12830 | 1/20 | 0.52 |
| ▸ | NPBWR1 | P48145 | 7/20 | 0.47 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.46 |
| ▸ | PDE1A | P54750 | 1/20 | 0.46 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.46 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10677550 | 0.78 | KDM4E (0.41) | BRD4BPTFNPBWR1PDE1APDE1B | |
| SCHEMBL10367314 | 0.78 | MTNR1A (0.45) | BRD4BPTFKDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL9726824 | 0.76 | PDE9A (0.49) | BRD4BPTFNPBWR1CYP3A4KMT2A | |
| SCHEMBL9726619 | 0.74 | BRD4 (0.49) | BRD4BPTFPOLBKMT2AKDM4E | |
| SCHEMBL9726895 | 0.74 | PDE9A (0.45) | BRD4BPTFNPBWR1GRM2PDE1A | |
| SCHEMBL10366891 | 0.74 | SMN1; SMN2 (0.51) | BRD4BPTFKMT2AKDM4ERAB9A | |
| SCHEMBL9726665 | 0.73 | BRD4 (0.48) | BRD4BPTFCYP3A4POLBKMT2A | |
| SCHEMBL9726673 | 0.71 | BRD4 (0.46) | BRD4BPTFPOLBKMT2AKDM4E | |
| SCHEMBL2551062 | 0.71 | NPBWR1 (0.77) | NPBWR1CYP3A4MCHR1KMT2ARAB9A | |
| SCHEMBL24640895 | 0.70 | NPBWR1 (0.54) | BRD4BPTFNPBWR1MCHR1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0193853-B1 | 3(2H)PYRIDAZINONE, PROCESS FOR ITS PREPARATION AND ANTI-ALLERGIC AGENT CONTAINING IT | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1990-09-12 | — | — | EP | disclosed |
| US-4783462-A | 3(2H)pyridazinone, and anti-allergic agent containing it | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1988-11-08 | — | — | US | disclosed |
| EP-0193853-A2 | 3(2H)pyridazinone, process for its preparation and anti-allergic agent containing it | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1986-09-10 | — | — | EP | disclosed |