Benzaldehyde

Benzaldehyde

SCHEMBL10366356

C=CCC(CC=C)C(=O)O.O=Cc1ccccc1

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.51
ALDH1A1 P00352 2/20 0.50
CYP2A6 P11509 1/20 0.50
GRIK1 P39086 6/20 0.44
GRIK2 Q13002 6/20 0.44
CPA1 P15085 3/20 0.43
TBXAS1 P24557 1/20 0.41
CYP1A2 P05177 1/20 0.41
KMT2A Q03164 1/20 0.39
TSHR P16473 1/20 0.39
UNG P13051 1/20 0.38
CPA3 P15088 2/20 0.37
FOLH1 Q04609 1/20 0.37
CPB1 P15086 1/20 0.37
CPB2 Q96IY4 1/20 0.37
CYP2D6 P10635 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13258634 0.83 GRIK1 (0.63) CYP2C19GRIK1GRIK2
SCHEMBL891727 0.78 GRIK1 (0.64) CYP2C19GRIK1GRIK2CPA1TBXAS1
Benzaldehyde SCHEMBL4311219 0.78 ALDH1A1 (0.54) ALDH1A1CYP2A6GRIK1GRIK2CYP1A2
Benzaldehyde SCHEMBL10397396 0.77 CYP2C19 (0.50) CYP2C19ALDH1A1CYP2A6TSHR
Benzaldehyde SCHEMBL28589859 0.77 ALDH1A1 (0.64) CYP2C19ALDH1A1CYP2A6KMT2ATSHR
SCHEMBL629350 0.76 CYP1A2 (0.68) CYP2C19CPA1CYP1A2CPA3FOLH1
SCHEMBL252900 0.76 CYP1A2 (0.68) CYP2C19CPA1CYP1A2CPA3FOLH1
SCHEMBL9007628 0.76 CYP1A2 (0.68) CYP2C19CPA1CYP1A2CPA3FOLH1
SCHEMBL1663075 0.76 CYP2C19 (0.49) CYP2C19ALDH1A1GRIK1GRIK2CPA1
SCHEMBL6402173 0.74 GRIK1 (0.55) CYP2C19GRIK1GRIK2CPA1TBXAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0237769-B1 BENZALDEHYDE-DIALKYL ACETALS BAYER AG (DE) 1990-04-04 EP disclosed
EP-0237769-A2 Benzaldehyde-dialkyl acetals BAYER AG (DE) 1987-09-23 EP disclosed