Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.42 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.42 |
| ▸ | CPA1 | P15085 | 2/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9352308 | 0.78 | TSHR (0.70) | CYP2C19TBXAS1TSHRGRIK1GRIK2 | |
| SCHEMBL3143553 | 0.77 | CYP2C19 (0.52) | CYP2C19TBXAS1TSHRGRIK1GRIK2 | |
| Benzaldehyde SCHEMBL10366356 | 0.76 | CYP2C19 (0.51) | CYP2C19TBXAS1TSHRGRIK1GRIK2 | |
| SCHEMBL9278355 | 0.75 | CYP2C19 (0.47) | CYP2C19TBXAS1TSHRGRIK1GRIK2 | |
| SCHEMBL891727 | 0.75 | GRIK1 (0.64) | CYP2C19TBXAS1TSHRGRIK1GRIK2 | |
| SCHEMBL629350 | 0.74 | CYP1A2 (0.68) | CYP2C19CPA1CYP1A2CPA3FOLH1 | |
| SCHEMBL9007628 | 0.74 | CYP1A2 (0.68) | CYP2C19CPA1CYP1A2CPA3FOLH1 | |
| SCHEMBL252900 | 0.74 | CYP1A2 (0.68) | CYP2C19CPA1CYP1A2CPA3FOLH1 | |
| SCHEMBL13258634 | 0.73 | GRIK1 (0.63) | CYP2C19GRIK1GRIK2 | |
| SCHEMBL28296019 | 0.73 | L3MBTL1 (0.56) | CYP2C19TBXAS1TSHRCYP1A2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011050284-A1 | PYRAZOLYLPYRIDINE ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-04-28 | — | — | WO | disclosed |