Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.35 |
| ▸ | BCHE | P06276 | 2/20 | 0.35 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.35 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7319281 | 0.91 | ADORA3 (0.47) | ALDH1A1KDM4EHRH3KCNH2CACNA1F | |
| SCHEMBL10366138 | 0.87 | CACNA1F (0.41) | CACNA1BDHODHHRH3KCNH2POLB | |
| SCHEMBL10368230 | 0.87 | ABCB1 (0.48) | MEN1KMT2ALMNACACNA1BALDH1A1 | |
| SCHEMBL10368228 | 0.87 | ABCB1 (0.48) | MEN1KMT2ALMNACACNA1BALDH1A1 | |
| SCHEMBL10367338 | 0.85 | ADORA3 (0.34) | MEN1KMT2ALMNADHODHKDM4E | |
| SCHEMBL7315909 | 0.79 | ABCB1 (0.57) | MEN1KMT2ALMNAHRH3KCNH2 | |
| SCHEMBL7313818 | 0.78 | ADRA2A (0.45) | KMT2ALMNAALDH1A1HRH3KCNH2 | |
| SCHEMBL10366377 | 0.76 | DRD3 (0.46) | CACNA1BKCNH2POLBMAPTCACNA1C | |
| SCHEMBL10366379 | 0.76 | DRD3 (0.46) | CACNA1BKCNH2POLBMAPTCACNA1C | |
| SCHEMBL10369237 | 0.74 | MEN1 (0.43) | MEN1KMT2ACACNA1BALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0177965-B1 | NOVEL OXA- AND THIADIAZOLYL DERIVATIVES AND THEIR USE | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1990-03-21 | — | — | EP | claimed |