Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1F | O60840 | 6/20 | 0.38 |
| ▸ | CACNA1D | Q01668 | 6/20 | 0.38 |
| ▸ | CACNA1S | Q13698 | 6/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 6/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7313818 | 0.88 | ADRA2A (0.45) | CACNA1FCACNA1DCACNA1SCACNA1CKCNH2 | |
| SCHEMBL10367338 | 0.88 | ADORA3 (0.34) | CACNA1FCACNA1DCACNA1SCACNA1CKCNH2 | |
| SCHEMBL10366138 | 0.85 | CACNA1F (0.41) | CACNA1FCACNA1DCACNA1SCACNA1CKCNH2 | |
| SCHEMBL10368511 | 0.84 | ABCB1 (0.46) | CACNA1FCACNA1DCACNA1SCACNA1CKCNH2 | |
| SCHEMBL7270521 | 0.79 | KMT2A (0.35) | CACNA1FCACNA1DCACNA1SCACNA1CADRA2A | |
| SCHEMBL7319281 | 0.75 | ADORA3 (0.47) | CACNA1FCACNA1DCACNA1SCACNA1CKCNH2 | |
| SCHEMBL7264445 | 0.73 | CACNA1F (0.41) | CACNA1FCACNA1DCACNA1SCACNA1CKMT2A | |
| SCHEMBL7265549 | 0.73 | CACNA1F (0.44) | CACNA1FCACNA1DCACNA1SCACNA1CALDH1A1 | |
| SCHEMBL10367146 | 0.73 | MEN1 (0.37) | CACNA1FCACNA1DCACNA1SCACNA1CKCNH2 | |
| SCHEMBL10368764 | 0.73 | KCNH2 (0.40) | CACNA1CKCNH2ADRA2AADRA1AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0177965-B1 | NOVEL OXA- AND THIADIAZOLYL DERIVATIVES AND THEIR USE | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1990-03-21 | — | — | EP | claimed |