Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | KLK7 | P49862 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | METAP1 | P53582 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CASR | P41180 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9530343 | 0.92 | POLB (0.36) | RAB9ANPSR1POLBSMN1; SMN2NPC1 | |
| SCHEMBL9527604 | 0.91 | FAAH (0.36) | RAB9APOLBSMN1; SMN2NPC1LMNA | |
| SCHEMBL9528551 | 0.89 | POLB (0.38) | RAB9ANPSR1POLBSMN1; SMN2NPC1 | |
| SCHEMBL9528238 | 0.88 | POLB (0.37) | RAB9ANPSR1POLBSMN1; SMN2NPC1 | |
| SCHEMBL9527618 | 0.88 | PKM (0.38) | RAB9ANPSR1POLBSMN1; SMN2NPC1 | |
| SCHEMBL9528908 | 0.86 | NCEH1 (0.41) | POLBKLK7KMT2AALDH1A1 | |
| SCHEMBL9528478 | 0.86 | ASAH1 (0.39) | RAB9APOLBSMN1; SMN2NPC1LMNA | |
| SCHEMBL9530047 | 0.85 | MAPT (0.34) | RAB9ANPSR1SMN1; SMN2ALOX5KLK7 | |
| SCHEMBL9528699 | 0.85 | HTT (0.39) | RAB9ANPSR1POLBSMN1; SMN2NPC1 | |
| SCHEMBL10368162 | 0.83 | METAP1 (0.37) | POLBSMN1; SMN2LMNAKDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0319170-B1 | ACYL DERIVATIVES OF HYDROXY PYRIMIDINES | PFIZER INC. (US) | 1993-03-17 | — | — | EP | claimed |
| US-4940712-A | Derivatives of hydroxyprimidines as leukotriene synthesis inhibitors | PFIZER INC. (US) | 1990-07-10 | — | — | US | claimed |
| EP-0319170-B1 | ACYL DERIVATIVES OF HYDROXY PYRIMIDINES | PFIZER INC. (US) | 1993-03-17 | — | — | EP | disclosed |
| US-4940712-A | Derivatives of hydroxyprimidines as leukotriene synthesis inhibitors | PFIZER INC. (US) | 1990-07-10 | — | — | US | disclosed |