Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.48 |
| ▸ | APP | P05067 | 3/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10368353 | 0.79 | OPRM1 (0.69) | OPRM1OPRK1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL10366782 | 0.78 | SIGMAR1 (0.53) | OPRM1OPRK1SIGMAR1 | |
| SCHEMBL5142329 | 0.76 | OPRM1 (0.61) | OPRM1OPRK1SIGMAR1 | |
| SCHEMBL9516955 | 0.75 | SIGMAR1 (0.67) | OPRM1OPRK1SIGMAR1 | |
| SCHEMBL8678608 | 0.73 | OPRM1 (0.98) | OPRM1OPRK1SIGMAR1 | |
| SCHEMBL10366240 | 0.71 | SIGMAR1 (0.56) | OPRM1OPRK1SIGMAR1BCHEMAPT | |
| SCHEMBL9269462 | 0.68 | KDM4E (0.52) | MAPT | |
| SCHEMBL27494378 | 0.68 | SIGMAR1 (0.75) | OPRM1OPRK1SIGMAR1MAPT | |
| SCHEMBL12925954 | 0.68 | EGFR (0.47) | MAPT | |
| SCHEMBL7647610 | 0.66 | SIGMAR1 (0.71) | OPRM1OPRK1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0147085-B1 | SUBSTITUTED TRANS-1.2-DIAMINOCYCLOHEXYL AMIDE COMPOUNDS | WARNER-LAMBERT COMPANY (US) | 1990-03-14 | — | — | EP | disclosed |