Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.67 |
| ▸ | LMNA | P02545 | 11/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.67 |
| ▸ | HPGD | P15428 | 9/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 7/20 | 0.67 |
| ▸ | MEN1 | O00255 | 7/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.67 |
| ▸ | HTT | P42858 | 6/20 | 0.67 |
| ▸ | HKDC1 | Q2TB90 | 5/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.67 |
| ▸ | CCR6 | P51684 | 3/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.64 |
| ▸ | RAB9A | P51151 | 3/20 | 0.64 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.64 |
| ▸ | TP53 | P04637 | 2/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.64 |
| ▸ | NPC1 | O15118 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | MPI | P34949 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9793743 | 0.84 | MAPT (0.60) | MAPTLMNAALDH1A1KDM4EHPGD | |
| SCHEMBL9793702 | 0.82 | MAPT (0.61) | MAPTLMNAALDH1A1KDM4EHPGD | |
| SCHEMBL10751474 | 0.81 | MAPT (0.64) | MAPTLMNAALDH1A1KDM4EHPGD | |
| SCHEMBL8285451 | 0.81 | MAPT (1.00) | MAPTLMNAALDH1A1KDM4EHPGD | |
| SCHEMBL9904910 | 0.79 | MAPT (0.87) | MAPTLMNAALDH1A1KDM4EHPGD | |
| SCHEMBL2489785 | 0.79 | MAPT (1.00) | MAPTLMNAALDH1A1KDM4EHPGD | |
| SCHEMBL17969781 | 0.78 | ALDH1A1 (0.78) | MAPTLMNAALDH1A1KDM4EHPGD | |
| SCHEMBL7538581 | 0.78 | PPARG (0.72) | MAPTLMNAALDH1A1KDM4EHPGD | |
| SCHEMBL8285454 | 0.78 | MAPT (1.00) | MAPTLMNAALDH1A1KDM4EHPGD | |
| SCHEMBL9904567 | 0.76 | MAPT (0.78) | MAPTLMNAALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0234931-B1 | AZAANTHRACENE COMPOUNDS | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1990-06-27 | — | — | EP | disclosed |
| EP-0234931-A1 | Azaanthracene compounds | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1987-09-02 | — | — | EP | disclosed |
| US-4472578-A | Benzo[a]phenazine antimicrobials | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1984-09-18 | — | — | US | disclosed |