SCHEMBL10751474

SCHEMBL10751474

CCOC(=O)C1=C(Cl)C(=O)c2ccccc2C1=O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 12/20 0.64
LMNA P02545 10/20 0.64
ALDH1A1 P00352 9/20 0.64
NPSR1 Q6W5P4 7/20 0.64
HPGD P15428 7/20 0.64
KDM4E B2RXH2 7/20 0.64
HKDC1 Q2TB90 5/20 0.64
ALOX12 P18054 4/20 0.64
CCR6 P51684 3/20 0.64
HSP90AA1 P07900 2/20 0.64
TNF P01375 1/20 0.64
RUNX1 Q01196 1/20 0.64
CBFB Q13951 1/20 0.64
NOD2 Q9HC29 1/20 0.64
GPR35 Q9HC97 1/20 0.64
NOD1 Q9Y239 1/20 0.64
SMN1; SMN2 Q16637 8/20 0.59
MEN1 O00255 7/20 0.59
KMT2A Q03164 7/20 0.59
TDP1 Q9NUW8 5/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10874730 0.82 ALDH1A1 (0.45) MAPTLMNAALDH1A1NPSR1HPGD
SCHEMBL9793702 0.82 MAPT (0.61) MAPTLMNAALDH1A1NPSR1HPGD
SCHEMBL10370782 0.81 MAPT (0.67) MAPTLMNAALDH1A1NPSR1HPGD
SCHEMBL13561203 0.80 HSP90AA1 (0.74) MAPTLMNAALDH1A1NPSR1HPGD
SCHEMBL8285456 0.79 MAPT (1.00) MAPTLMNAALDH1A1NPSR1HPGD
SCHEMBL9793743 0.78 MAPT (0.60) MAPTLMNAALDH1A1NPSR1HPGD
SCHEMBL7538581 0.78 PPARG (0.72) MAPTLMNAALDH1A1NPSR1HPGD
SCHEMBL17969781 0.78 ALDH1A1 (0.78) MAPTLMNAALDH1A1NPSR1HPGD
SCHEMBL11058279 0.76 LMNA (0.46) MAPTLMNAALDH1A1NPSR1HPGD
SCHEMBL9904567 0.76 MAPT (0.78) MAPTLMNAALDH1A1NPSR1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4636456-A EXPOSURE, SILVER HALIDE EMULSIONS, HYDROQUINONE OR ESTER OR CARBONATE, DEVELOPMENT INHIBITORS FUJI PHOTO FILM CO., LTD. (JP) 1987-01-13 US disclosed