SCHEMBL10374358

SCHEMBL10374358

CCC(Br)C(=O)NCc1ccccc1C

nearest known ligand 0.59

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.59
ALDH1A1 P00352 7/20 0.54
HPGD P15428 3/20 0.54
GAA P10253 2/20 0.50
KMT2A Q03164 2/20 0.50
HTT P42858 1/20 0.50
PPARG P37231 1/20 0.49
POLB P06746 1/20 0.49
MEN1 O00255 1/20 0.49
PKM P14618 1/20 0.49
KDM4E B2RXH2 2/20 0.49
EPHX2 P34913 1/20 0.47
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9424898 0.83 ALDH1A1 (0.73) ALDH1A1KMT2AHTTMEN1KDM4E
SCHEMBL27472283 0.83 RIPK1 (0.55) LMNAALDH1A1HPGD
SCHEMBL10374270 0.83 LMNA (0.57) LMNAALDH1A1HPGDGAAKMT2A
SCHEMBL12757441 0.82 LMNA (0.63) LMNAALDH1A1HPGDGAAKMT2A
SCHEMBL23754579 0.79 KMT2A (0.55) ALDH1A1GAAKMT2APOLBMEN1
SCHEMBL2936657 0.79 KMT2A (0.55) ALDH1A1GAAKMT2APOLBMEN1
SCHEMBL8380278 0.79 LMNA (0.53) LMNAALDH1A1HPGDGAAKMT2A
SCHEMBL2749189 0.76 LMNA (0.69) LMNAALDH1A1HPGDGAAKMT2A
SCHEMBL2017132 0.76 ALDH1A1 (0.73) LMNAALDH1A1HPGDGAAKMT2A
SCHEMBL24576210 0.76 ALDH1A1 (0.68) LMNAALDH1A1HPGDGAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0212969-B1 PYRIMIDINYLOXYALKANAMIDE DERIVATIVE AND HERBICIDE COMPOSITION CONTAINING THE SAME UBE INDUSTRIES, LTD. (JP) 1990-05-30 EP disclosed
US-4747866-A Pyrimidinyloxyalkanamide derivatives and herbicide composition containing the same UBE INDUSTRIES, LTD. (JP) 1988-05-31 US disclosed
EP-0212969-A1 Pyrimidinyloxyalkanamide derivative and herbicide composition containing the same UBE INDUSTRIES, LTD. (JP) 1987-03-04 EP disclosed