Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MMP8 | P22894 | 1/20 | 0.51 |
| ▸ | MME | P08473 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | ANPEP | P15144 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA3 | P07451 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.50 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23754579 | 1.00 | KMT2A (0.55) | KMT2AMEN1GAAMMP8MME | |
| SCHEMBL10638067 | 0.87 | KMT2A (0.53) | KMT2AMEN1MMP8MMEALDH1A1 | |
| SCHEMBL26451372 | 0.85 | KMT2A (0.60) | KMT2AMEN1GAAALDH1A1ANPEP | |
| SCHEMBL526281 | 0.84 | KMT2A (0.53) | KMT2AMEN1GAAMMP8MME | |
| SCHEMBL8514567 | 0.84 | KMT2A (0.53) | KMT2AMEN1GAAMMP8MME | |
| SCHEMBL526555 | 0.84 | KMT2A (0.53) | KMT2AMEN1GAAMMP8MME | |
| SCHEMBL9276843 | 0.84 | KMT2A (0.57) | KMT2AMEN1GAAMMP8MME | |
| SCHEMBL27554760 | 0.83 | HPGD (0.54) | KMT2AMEN1GAAALDH1A1ANPEP | |
| SCHEMBL23775683 | 0.83 | POLB (0.66) | KMT2AMEN1POLBALDH1A1MAPT | |
| SCHEMBL13608946 | 0.82 | KMT2A (0.67) | KMT2AMEN1GAAMMP8MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230137023-A1 | PROCESS FOR PREPARING S-BEFLUBUTAMID BY RESOLVING 2-BROMOBUTANOIC ACID | CHEMINOVA A/S (DK) | 2023-05-04 | — | — | US | disclosed |
| US-20230137023-A1 | PROCESS FOR PREPARING S-BEFLUBUTAMID BY RESOLVING 2-BROMOBUTANOIC ACID | CHEMINOVA A/S (DK) | 2023-05-04 | — | — | US | disclosed |
| US-20230137023-A1 | PROCESS FOR PREPARING S-BEFLUBUTAMID BY RESOLVING 2-BROMOBUTANOIC ACID | CHEMINOVA A/S (DK) | 2023-05-04 | — | — | US | disclosed |
| US-20230117284-A1 | PROCESS FOR THE SYNTHESIS OF S-BEFLUBUTAMID FROM (R)-2-AMINOBUTANOIC ACID | CHEMINOVA A/S (DK) | 2023-04-20 | — | — | US | disclosed |
| EP-4103538-A1 | PROCESS FOR PREPARING S-BEFLUBUTAMID BY RESOLVING 2-BROMOBUTANOIC ACID | Cheminova A/S (DK) | 2022-12-21 | — | — | EP | disclosed |
| CN-115103829-A | Method for preparing S-fluorobutachlor by resolving 2-bromobutyric acid | 凯米诺瓦有限公司 | 2022-09-23 | — | — | CN | disclosed |
| CN-115087633-A | Method for synthesizing S-fluorobutachlor from (R) -2-aminobutyric acid | 凯米诺瓦有限公司 | 2022-09-20 | — | — | CN | disclosed |
| WO-2021161100-A1 | PROCESS FOR PREPARING S-BEFLUBUTAMID BY RESOLVING 2-BROMOBUTANOIC ACID | CHEMINOVA A/S (DK) | 2021-08-19 | — | — | WO | disclosed |
| US-8946476-B2 | Process for the preparation of amino acid derivatives | UCB PHARMA GMBH (DE) | 2015-02-03 | — | — | US | disclosed |
| US-20110263899-A1 | Novel Process for the Preparation of Amino Acid Derivatives | UCB PHARMA GMBH (DE) | 2011-10-27 | — | — | US | disclosed |
| EP-1836163-B1 | PYRROLIDINE DERIVATIVES FOR THE TREATMENT OF A DISEASE DEPENDING ON THE ACTIVITY OF RENIN | NOVARTIS AG (CH) | 2010-09-22 | — | — | EP | disclosed |
| US-20100087427-A1 | PYRROLIDINE DERIVATIVES FOR THE TREATMENT OF A DISEASE DEPENDING ON THE ACTIVITY OF RENIN | BREITENSTEIN WERNER | 2010-04-08 | — | — | US | disclosed |
| CN-101115715-A | Pyrrolidine derivatives for the treatment of diseases associated with renin activity | NOVARTIS AG (CH) | 2008-01-30 | — | — | CN | disclosed |
| EP-1836163-A2 | PYRROLIDINE DERIVATIVES FOR THE TREATMENT OF A DISEASE DEPENDING ON THE ACTIVITY OF RENIN | Novartis AG (CH) | 2007-09-26 | — | — | EP | disclosed |
| WO-2006066896-A2 | PYRROLIDINE DERIVATIVES FOR THE TREATMENT OF A DISEASE DEPENDING ON THE ACTIVITY OF RENIN | NOVARTIS AG (CH) | 2006-06-29 | — | — | WO | disclosed |
| EP-0427445-B1 | Benzylideneaminoxyalkanoic acid (thio) amide derivative, process for preparing the same and herbicide | UBE INDUSTRIES (JP) | 1994-06-08 | — | — | EP | disclosed |
| US-5314865-A | Certain alkylidine aminooxyamide compounds useful as herbicides | ICI AMERICAS INC. (US) | 1994-05-24 | — | — | US | disclosed |
| EP-0427445-A1 | Benzylideneaminoxyalkanoic acid (thio) amide derivative, process for preparing the same and herbicide | UBE INDUSTRIES, LTD. (JP) | 1991-05-15 | — | — | EP | disclosed |
| US-5002605-A | Herbicides | ICI AMERICAS INC. (US) | 1991-03-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087427-A1 | PYRROLIDINE DERIVATIVES FOR THE TREATMENT OF A DISEASE DEPENDING ON THE ACTIVITY OF RENIN | REN, ACE, PEPD | KMT2A 3722/4885MEN1 1437/4885GAA 84/4885 |
| US-20230117284-A1 | PROCESS FOR THE SYNTHESIS OF S-BEFLUBUTAMID FROM (R)-2-AMINOBUTANOIC ACID | SRM, SCN1B, SUCNR1 | KMT2A 2698/4885MEN1 2042/4885GAA 2502/4885 |
| US-20110263899-A1 | Novel Process for the Preparation of Amino Acid Derivatives | BCAT2, DNPEP, NPEPPS | KMT2A 514/4885MEN1 3770/4885GAA 1062/4885 |
| US-20230137023-A1 | PROCESS FOR PREPARING S-BEFLUBUTAMID BY RESOLVING 2-BROMOBUTANOIC ACID | RAC2, RAC1, RAC3 | KMT2A 4178/4885MEN1 1417/4885GAA 3983/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.