Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | SCN1A | P35498 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10625 | 0.94 | HRH3 (0.61) | SMN1; SMN2GAANPC1RAB9AALDH1A1 | |
| SCHEMBL10636 | 0.83 | HRH3 (0.61) | HRH3MEN1KMT2AKCNH2MAPT | |
| SCHEMBL22773340 | 0.79 | SMN1; SMN2 (0.74) | SMN1; SMN2GAANPC1RAB9AALDH1A1 | |
| SCHEMBL23742277 | 0.78 | ALDH1A1 (0.66) | SMN1; SMN2GAANPC1RAB9AALDH1A1 | |
| SCHEMBL23742316 | 0.77 | ALDH1A1 (0.85) | SMN1; SMN2GAANPC1RAB9AALDH1A1 | |
| SCHEMBL7337992 | 0.76 | ALDH1A1 (0.51) | SMN1; SMN2GAANPC1RAB9AALDH1A1 | |
| SCHEMBL3007594 | 0.76 | GAA (0.71) | SMN1; SMN2GAANPC1RAB9AALDH1A1 | |
| SCHEMBL104326 | 0.75 | MEN1 (0.70) | SMN1; SMN2GAANPC1RAB9AALDH1A1 | |
| SCHEMBL18044489 | 0.75 | SRC (0.59) | SMN1; SMN2GAANPC1RAB9AALDH1A1 | |
| SCHEMBL10377 | 0.75 | NPC1 (0.58) | SMN1; SMN2GAANPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2488489-A2 | C-LINKED HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | Pfizer Inc. (US) | 2012-08-22 | — | — | EP | disclosed |
| WO-2011045703-A2 | C-LINKED HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | PFIZER INC. (US) | 2011-04-21 | — | — | WO | disclosed |