Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 16/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.60 |
| ▸ | HRH1 | P35367 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10625 | 0.89 | HRH3 (0.61) | HRH3KCNH2HRH1MEN1KMT2A | |
| SCHEMBL10376 | 0.83 | SMN1; SMN2 (0.58) | HRH3KCNH2MEN1KMT2AMAPT | |
| SCHEMBL12050645 | 0.78 | HRH3 (1.00) | HRH3KCNH2HRH1HRH4 | |
| SCHEMBL4094339 | 0.78 | HRH3 (1.00) | HRH3KCNH2HRH1HRH4 | |
| SCHEMBL12050718 | 0.77 | HRH3 (0.96) | HRH3KCNH2HRH1HRH4 | |
| SCHEMBL491796 | 0.76 | ALDH1A1 (0.84) | HRH3KCNH2MEN1KMT2A | |
| SCHEMBL5327477 | 0.76 | MMP9 (0.62) | POLB | |
| SCHEMBL5856173 | 0.75 | ALDH1A1 (0.82) | HRH3KCNH2MEN1KMT2A | |
| SCHEMBL12050724 | 0.75 | HRH3 (0.75) | HRH3KCNH2HRH1POLBMAPT | |
| SCHEMBL10637 | 0.75 | HRH3 (0.76) | HRH3KCNH2HRH1HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2488489-A2 | C-LINKED HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | Pfizer Inc. (US) | 2012-08-22 | — | — | EP | disclosed |
| WO-2011045703-A2 | C-LINKED HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | PFIZER INC. (US) | 2011-04-21 | — | — | WO | disclosed |