Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.58 |
| ▸ | HTR2A | P28223 | 1/20 | 0.58 |
| ▸ | SCN1A | P35498 | 1/20 | 0.58 |
| ▸ | HTR2B | P41595 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.58 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | HRH2 | P25021 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10376 | 0.94 | SMN1; SMN2 (0.58) | HRH3ALDH1A1MAPK1CYP1A2CHRM2 | |
| SCHEMBL10636 | 0.89 | HRH3 (0.61) | HRH3KCNH2KMT2AMEN1HRH1 | |
| SCHEMBL27896953 | 0.80 | HRH3 (0.76) | HRH3ALDH1A1MAPK1CYP1A2CHRM2 | |
| SCHEMBL14714478 | 0.77 | HRH3 (0.77) | HRH3ALDH1A1MAPK1CYP1A2CHRM2 | |
| SCHEMBL10626 | 0.76 | HRH3 (0.63) | HRH3ALDH1A1MAPK1CYP1A2CHRM2 | |
| SCHEMBL29973108 | 0.76 | HRH3 (0.69) | HRH3ALDH1A1MAPK1CYP1A2CHRM2 | |
| SCHEMBL15577570 | 0.76 | MEN1 (0.54) | HRH3ALDH1A1MAPK1CYP1A2CHRM2 | |
| SCHEMBL10223326 | 0.76 | MEN1 (0.77) | HRH3ALDH1A1MAPK1CYP1A2CHRM2 | |
| SCHEMBL14724514 | 0.76 | HRH3 (0.71) | HRH3ALDH1A1MAPK1CYP1A2CHRM2 | |
| Pramoxine SCHEMBL26020 | 0.75 | ALDH1A1 (1.00) | HRH3ALDH1A1MAPK1CYP1A2CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2488489-A2 | C-LINKED HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | Pfizer Inc. (US) | 2012-08-22 | — | — | EP | disclosed |
| WO-2011045703-A2 | C-LINKED HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | PFIZER INC. (US) | 2011-04-21 | — | — | WO | disclosed |