Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | PDE4A | P27815 | 3/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12957537 | 1.00 | CYP3A4 (0.46) | CYP3A4NR3C1TSHRMEN1KMT2A | |
| SCHEMBL4438143 | 1.00 | CYP3A4 (0.46) | CYP3A4NR3C1TSHRMEN1KMT2A | |
| SCHEMBL2069332 | 0.98 | NR3C1 (0.48) | CYP3A4NR3C1TSHRMEN1KMT2A | |
| SCHEMBL2069096 | 0.98 | NR3C1 (0.48) | CYP3A4NR3C1TSHRMEN1KMT2A | |
| SCHEMBL2069182 | 0.88 | CYP3A4 (0.38) | CYP3A4NR3C1TSHRMEN1KMT2A | |
| SCHEMBL2069577 | 0.88 | CYP3A4 (0.38) | CYP3A4NR3C1TSHRMEN1KMT2A | |
| SCHEMBL7499651 | 0.86 | CYP3A4 (0.41) | CYP3A4NR3C1TSHRMEN1KMT2A | |
| SCHEMBL2071317 | 0.85 | LMNA (0.37) | CYP3A4NR3C1KMT2AALDH1A1MAPT | |
| SCHEMBL2072015 | 0.85 | LMNA (0.37) | CYP3A4NR3C1KMT2AALDH1A1MAPT | |
| SCHEMBL2072017 | 0.85 | LMNA (0.37) | CYP3A4NR3C1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1861402-B1 | ISOFLAVONOID DIMERS | NOVOGEN RES PTY LTD (AU) | 2011-01-26 | — | — | EP | disclosed |
| US-7700644-B2 | Such as 4,9-Dihydroxy-14,15-dimethoxy-12a-(3',4'-dimethoxyphenyl)-2, 11-dioxa-(1H,12H)-6b,6c,12a,16b-tetrahydronaphtho[1,2-g]chrysene via dimerisation of 3-phenylchroman | NOVOGEN RESEARCH PTY LTD (AU) | 2010-04-20 | — | — | US | disclosed |
| US-20090233999-A1 | COMPOSITIONS AND THERAPEUTIC METHODS INVOLVING ISOFLAVONES AND ANALOGUES THEREOF | NOVOGEN RESEARCH PTY LTD (AU) | 2009-09-17 | — | — | US | disclosed |
| US-20080306140-A1 | Isoflavonoid Dimers | NOVOGEN RESEARCH PTY LTD (AU) | 2008-12-11 | — | — | US | disclosed |
| EP-1861402-A1 | ISOFLAVONOID DIMERS | Novogen Research Pty. Ltd. (AU) | 2007-12-05 | — | — | EP | disclosed |
| WO-2006099681-A1 | ISOFLAVONOID DIMERS | NOVOGEN RESEARCH PTY LTD (AU) | 2006-09-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233999-A1 | COMPOSITIONS AND THERAPEUTIC METHODS INVOLVING ISOFLAVONES AND ANALOGUES THEREOF | SHBG, OAT, APOB | CYP3A4 2407/4885NR3C1 1431/4885TSHR 4750/4885 |
| US-20080306140-A1 | Isoflavonoid Dimers | CDK2, CDK20, F2 | CYP3A4 269/4885NR3C1 3208/4885TSHR 4145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.