Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 5/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | ADH1C | P00326 | 1/20 | 0.34 |
| ▸ | ADH1A | P07327 | 1/20 | 0.34 |
| ▸ | ADH4 | P08319 | 1/20 | 0.34 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25045520 | 0.79 | DNM1 (0.44) | DNM1PLA2G1BPLA2G2ATSHRTHRB | |
| SCHEMBL268149 | 0.78 | DNM1 (0.39) | DNM1TSHRTHRBMGLLCA12 | |
| SCHEMBL1038114 | 0.78 | LMNA (0.42) | DNM1TSHRCA12CA1CA2 | |
| SCHEMBL190294 | 0.78 | LMNA (0.42) | DNM1TSHRCA12CA1CA2 | |
| SCHEMBL20590751 | 0.77 | DNM1 (0.48) | DNM1PLA2G1BPLA2G2ATSHRTHRB | |
| SCHEMBL1252854 | 0.77 | FDPS (0.35) | — | |
| Fluoride SCHEMBL11099490 | 0.77 | LMNA (0.46) | DNM1TSHRCA12CA1CA2 | |
| Fluoride SCHEMBL3259338 | 0.77 | LMNA (0.41) | DNM1TSHRCA12CA1CA2 | |
| SCHEMBL20142667 | 0.76 | DNM1 (0.46) | DNM1PLA2G1BPLA2G2ATSHRTHRB | |
| SCHEMBL17430697 | 0.76 | DNM1 (0.40) | DNM1PLA2G1BPLA2G2ATSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990003365-A1 | DIQUATERNARY NITROGEN COMPOUNDS | GAF CHEMICALS CORPORATION (US) | 1990-04-05 | — | — | WO | disclosed |