Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 15/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10380233 | 0.90 | FFAR4 (0.41) | FFAR4CYP11B1CYP11B2GRIN2BDGAT1 | |
| SCHEMBL14969247 | 0.80 | CYP11B1 (0.38) | FFAR4CYP11B1CYP11B2GRIN2BDGAT1 | |
| SCHEMBL14969248 | 0.80 | CYP11B1 (0.38) | FFAR4CYP11B1CYP11B2GRIN2BDGAT1 | |
| SCHEMBL10324875 | 0.80 | MELK (0.40) | FFAR4GPR119GRIN2BAOC3 | |
| SCHEMBL10379959 | 0.78 | DGAT1 (0.47) | DGAT1 | |
| SCHEMBL10379629 | 0.76 | FFAR4 (0.37) | FFAR4GPR119AOC3DGAT1 | |
| SCHEMBL10325156 | 0.76 | DGAT1 (0.38) | CYP11B1CYP11B2GRIN2BDGAT1 | |
| SCHEMBL10380087 | 0.76 | DGAT1 (0.59) | DGAT1 | |
| SCHEMBL4396258 | 0.76 | GAA (0.42) | FFAR4AOC3DGAT1 | |
| SCHEMBL10379966 | 0.76 | USP14 (0.44) | FFAR4DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012096813-A1 | IMIDAZOLE DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2012-07-19 | — | — | WO | disclosed |