Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR1 | P21462 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HBB | P68871 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1035595 | 0.88 | NR3C1 (0.34) | ALDH1A1LMNAALOX15TSHRMAPK1 | |
| SCHEMBL1037357 | 0.86 | FPR1 (0.36) | FPR1 | |
| SCHEMBL30042076 | 0.83 | SMN1; SMN2 (0.34) | ALDH1A1LMNATSHRHSD17B10 | |
| SCHEMBL1032996 | 0.83 | SMN1; SMN2 (0.34) | ALDH1A1LMNATSHRHSD17B10 | |
| SCHEMBL4326896 | 0.83 | FPR1 (0.31) | FPR1 | |
| SCHEMBL1035959 | 0.83 | FPR1 (0.30) | FPR1 | |
| SCHEMBL1965136 | 0.83 | FPR1 (0.33) | FPR1ALDH1A1LMNAALOX15TSHR | |
| SCHEMBL4326899 | 0.82 | FPR1 (0.31) | FPR1 | |
| SCHEMBL30041413 | 0.82 | AURKA (0.32) | — | |
| SCHEMBL1038477 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110160062-A1 | PYRAZOLE COMPOUNDS, PROCESS FOR THEIR PRODUCTION AND HERBICIDES CONTAINING THEM | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2011-06-30 | — | — | US | claimed |
| EP-2276743-A1 | PYRAZOLE COMPOUNDS, PROCESS FOR THEIR PRODUCTION AND HERBICIDES CONTAINING THEM | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2011-01-26 | — | — | EP | claimed |
| WO-2009142318-A1 | PYRAZOLE COMPOUNDS, PROCESS FOR THEIR PRODUCTION AND HERBICIDES CONTAINING THEM | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2009-11-26 | — | — | WO | claimed |
| US-8466089-B2 | Pyrazole compounds, process for their production and herbicides containing them | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2013-06-18 | — | — | US | disclosed |
| US-20110160062-A1 | PYRAZOLE COMPOUNDS, PROCESS FOR THEIR PRODUCTION AND HERBICIDES CONTAINING THEM | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2011-06-30 | — | — | US | disclosed |
| EP-2276743-A1 | PYRAZOLE COMPOUNDS, PROCESS FOR THEIR PRODUCTION AND HERBICIDES CONTAINING THEM | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2011-01-26 | — | — | EP | disclosed |
| WO-2009142318-A1 | PYRAZOLE COMPOUNDS, PROCESS FOR THEIR PRODUCTION AND HERBICIDES CONTAINING THEM | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2009-11-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110160062-A1 | PYRAZOLE COMPOUNDS, PROCESS FOR THEIR PRODUCTION AND HERBICIDES CONTAINING THEM | ARSA, AADAC, PDXK | FPR1 2116/4885ALDH1A1 790/4885LMNA 4746/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.