Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR1 | P21462 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 3/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HBB | P68871 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4584263 | 0.89 | NR3C1 (0.34) | ALDH1A1KDM4E | |
| SCHEMBL1882297 | 0.84 | SMN1; SMN2 (0.35) | ADORA3ADORA2AADORA1ALDH1A1KDM4E | |
| SCHEMBL10035244 | 0.83 | HTR1A (0.33) | ALDH1A1KDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL1038432 | 0.83 | FPR1 (0.32) | FPR1ALDH1A1LMNAALOX15TSHR | |
| SCHEMBL10035238 | 0.81 | — | — | |
| SCHEMBL10035234 | 0.79 | ABCB1 (0.36) | LMNASMN1; SMN2HTT | |
| SCHEMBL1882782 | 0.79 | PDE5A (0.36) | ALDH1A1KDM4ELMNATSHRMAPK1 | |
| SCHEMBL1965015 | 0.78 | SYK (0.32) | — | |
| SCHEMBL14570900 | 0.78 | SYK (0.34) | — | |
| SCHEMBL14124742 | 0.78 | ABCB1 (0.33) | ALDH1A1LMNATSHRMAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9801374-B2 | Active compound combinations comprising carboxamide derivatives | BAYER CROPSCIENCE AG (DE) | 2017-10-31 | — | — | US | disclosed |
| US-20150245610-A1 | ACTIVE COMPOUND COMBINATIONS COMPRISING CARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2015-09-03 | — | — | US | disclosed |
| EP-2908639-A1 | ACTIVE COMPOUND COMBINATIONS COMPRISING CARBOXAMIDE DERIVATIVES | Bayer Cropscience AG (DE) | 2015-08-26 | — | — | EP | disclosed |
| US-9102623-B2 | Pyridinecarboxamides, useful-plant-protecting composition comprising them and processes for their preparation and their use | BAYER CROPSCIENCE AG (DE) | 2015-08-11 | — | — | US | disclosed |
| EP-2144879-B1 | PYRIDON CARBOXAMIDES, AGENTS CONTAINING THESE BUT NOT IMPACTING USEFUL PLANTS AND METHOD FOR THEIR MANUFACTURE AND APPLICATION | BAYER IP GMBH (DE) | 2015-04-08 | — | — | EP | disclosed |
| WO-2014060502-A1 | ACTIVE COMPOUND COMBINATIONS COMPRISING CARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2014-04-24 | — | — | WO | disclosed |
| US-20120252670-A1 | PYRIDINECARBOXAMIDES, USEFUL-PLANT-PROTECTING COMPOSITION COMPRISING THEM AND PROCESSES FOR THEIR PREPARATION AND THEIR USE | ZIEMER FRANK (DE) | 2012-10-04 | — | — | US | disclosed |
| US-20110143939-A1 | QUINOXALIN-2-ONE DERIVATIVES, COMPOSITIONS WHICH PROTECT USEFUL PLANTS AND COMPRISE THESE DERIVATIVES, AND PROCESSES FOR THEIR PREPARATION AND THEIR USE | BAYER CROPSCIENCE AG (DE) | 2011-06-16 | — | — | US | disclosed |
| CN-1949966-B | Quinoxalin-2-one derivatives, crop protection agents comprising the same and method for production and use therof | BAYER CROPSCIENCE GMBH | 2010-05-26 | — | — | CN | disclosed |
| EP-1987717-A1 | Pyridon carboxamides, agents containing these but not impacting useful plants and method for their manufacture and application | Bayer CropScience AG (DE) | 2008-11-05 | — | — | EP | disclosed |
| EP-1987718-A1 | Utilisation of pyridine-2-oxy-3-carbon amides as safener | Bayer CropScience AG (DE) | 2008-11-05 | — | — | EP | disclosed |
| US-20080269059-A1 | PYRIDINECARBOXAMIDES, USEFUL-PLANT-PROTECTING COMPOSITION COMPRISING THEM AND PROCESSES FOR THEIR PREPARTION AND THEIR USE | BAYER CROPSCIENCE AG (DE) | 2008-10-30 | — | — | US | disclosed |
| US-20080269052-A1 | USE of PYRIDINE-2-OXY-3-CARBOXAMIDES AS SAFENERS | BAYER CROPSCIENCE AG (DE) | 2008-10-30 | — | — | US | disclosed |
| US-7396939-B2 | 3-cyclopropyl-4-(3-amino-2-methylbenzoyl)pyrazoles and their use as herbicides | BAYER CROPSCIENCE GMBH (DE) | 2008-07-08 | — | — | US | disclosed |
| CN-1949966-A | Quinoxalin-2-one derivatives, crop protection agents comprising the same and method for production and use therof | BAYER CROPSCIENCE GMBH (DE) | 2007-04-18 | — | — | CN | disclosed |
| EP-1746880-A1 | QUINOXALIN-2-ONE DERIVATIVES CROP PROTECTION AGENTS COMPRISING THE SAME AND METHOD FOR PRODUCTION AND USE THEROF | Bayer CropScience GmbH (DE) | 2007-01-31 | — | — | EP | disclosed |
| WO-2005112630-A1 | QUINOXALIN-2-ONE DERIVATIVES CROP PROTECTION AGENTS COMPRISING THE SAME AND METHOD FOR PRODUCTION AND USE THEROF | BAYER CROPSCIENCE GMBH (DE) | 2005-12-01 | — | — | WO | disclosed |
| US-20050256000-A1 | Quinoxalin-2-one derivatives, compositions which protect useful plants and comprise these derivatives, and processes for their preparation and their use | BAYER CROPSCIENCE GMBH (DE) | 2005-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269052-A1 | USE of PYRIDINE-2-OXY-3-CARBOXAMIDES AS SAFENERS | CBR3, CBR1, CYP4Z1 | FPR1 2849/4885ADORA3 1730/4885ADORA2A 2166/4885 |
| US-20050256000-A1 | Quinoxalin-2-one derivatives, compositions which protect useful plants and comprise these derivatives, and processes for their preparation and their use | QSOX1, CYC1, CBR3 | FPR1 1055/4885ADORA3 1413/4885ADORA2A 1903/4885 |
| US-20110143939-A1 | QUINOXALIN-2-ONE DERIVATIVES, COMPOSITIONS WHICH PROTECT USEFUL PLANTS AND COMPRISE THESE DERIVATIVES, AND PROCESSES FOR THEIR PREPARATION AND THEIR USE | QSOX1, PRDX2, NQO2 | FPR1 1822/4885ADORA3 2966/4885ADORA2A 2168/4885 |
| US-20120252670-A1 | PYRIDINECARBOXAMIDES, USEFUL-PLANT-PROTECTING COMPOSITION COMPRISING THEM AND PROCESSES FOR THEIR PREPARATION AND THEIR USE | CYC1, CYCS, CBR3 | FPR1 3610/4885ADORA3 1178/4885ADORA2A 1490/4885 |
| US-20080269059-A1 | PYRIDINECARBOXAMIDES, USEFUL-PLANT-PROTECTING COMPOSITION COMPRISING THEM AND PROCESSES FOR THEIR PREPARTION AND THEIR USE | CYC1, PYCR1, CBR3 | FPR1 3633/4885ADORA3 1363/4885ADORA2A 1544/4885 |
| US-20150245610-A1 | ACTIVE COMPOUND COMBINATIONS COMPRISING CARBOXAMIDE DERIVATIVES | AADAC, PFAS, CBR3 | FPR1 681/4885ADORA3 2395/4885ADORA2A 2409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.