SCHEMBL1032996

SCHEMBL1032996

CCn1ncc(C(=O)c2ccc(S(C)(=O)=O)c(OCCOC)c2C)c1O

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.34
RAB9A P51151 2/20 0.34
LMNA P02545 1/20 0.34
GAA P10253 2/20 0.33
ALDH1A1 P00352 2/20 0.33
HTT P42858 1/20 0.33
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
TSHR P16473 1/20 0.32
KMT2A Q03164 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
HSD17B10 Q99714 1/20 0.32
CYP1A2 P05177 1/20 0.31
CYP2C19 P33261 1/20 0.31
BTK Q06187 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30042076 1.00 SMN1; SMN2 (0.34) SMN1; SMN2RAB9ALMNAGAAALDH1A1
SCHEMBL1034518 0.92
SCHEMBL1738355 0.90 SMN1; SMN2 (0.36) SMN1; SMN2RAB9ALMNAGAAALDH1A1
SCHEMBL29002975 0.89 SMN1; SMN2 (0.33) SMN1; SMN2RAB9ALMNAGAAALDH1A1
SCHEMBL645624 0.88 NR3C1 (0.31)
SCHEMBL1037206 0.85 FPR1 (0.32)
SCHEMBL9078155 0.84 LMNA (0.33) SMN1; SMN2RAB9ALMNAGAAALDH1A1
SCHEMBL18074950 0.84 ALDH1A1 (0.30) SMN1; SMN2GAAALDH1A1HTT
SCHEMBL17396886 0.84 GAA (0.32) SMN1; SMN2LMNAGAAALDH1A1HTT
SCHEMBL26103122 0.84 SMN1; SMN2 (0.32) SMN1; SMN2RAB9ALMNAGAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1963274-B1 BENZOYLPYRAZOLE COMPOUNDS AND HERBICIDES CONTAINING THEM ISHIHARA SANGYO KAISHA (JP) 2015-04-29 EP claimed
EP-2546240-A1 Benzoylpyrazole compounds and herbicides containing them ISHIHARA SANGYO KAISHA, LTD. (JP) 2013-01-16 EP claimed
US-20110160062-A1 PYRAZOLE COMPOUNDS, PROCESS FOR THEIR PRODUCTION AND HERBICIDES CONTAINING THEM ISHIHARA SANGYO KAISHA, LTD. (JP) 2011-06-30 US claimed
EP-2276743-A1 PYRAZOLE COMPOUNDS, PROCESS FOR THEIR PRODUCTION AND HERBICIDES CONTAINING THEM ISHIHARA SANGYO KAISHA, LTD. (JP) 2011-01-26 EP claimed
WO-2009142318-A1 PYRAZOLE COMPOUNDS, PROCESS FOR THEIR PRODUCTION AND HERBICIDES CONTAINING THEM ISHIHARA SANGYO KAISHA, LTD. (JP) 2009-11-26 WO claimed
CN-115279738-B Pyrazole carboxylic ester compound and application thereof 沈阳中化农药化工研发有限公司 2023-12-19 CN disclosed
US-20230138225-A1 PYRAZOLE CARBOXYLATE ESTER COMPOUND AND USE THEREOF JIANGSU YANGNONG CHEMICAL CO., LTD. (CN) 2023-05-04 US disclosed
US-20230138225-A1 PYRAZOLE CARBOXYLATE ESTER COMPOUND AND USE THEREOF JIANGSU YANGNONG CHEMICAL CO., LTD. (CN) 2023-05-04 US disclosed
EP-4119545-A1 PYRAZOLE CARBOXYLATE COMPOUND AND USE THEREOF Shenyang Sinochem Agrochemicals R & D Co., Ltd. (CN) 2023-01-18 EP disclosed
EP-2365754-B1 HERBICIDAL COMPOSITIONS CONTAINING BENZOYLPYRAZOLE COMPOUNDS ISHIHARA SANGYO KAISHA (JP) 2016-09-21 EP disclosed
EP-3023006-A1 HERBICIDAL COMPOSITION ISHIHARA SANGYO KAISHA, LTD. (JP) 2016-05-25 EP disclosed
EP-1963274-B1 BENZOYLPYRAZOLE COMPOUNDS AND HERBICIDES CONTAINING THEM ISHIHARA SANGYO KAISHA (JP) 2015-04-29 EP disclosed
WO-2010067895-A1 HERBICIDAL COMPOSITIONS CONTAINING BENZOYLPYRAZOLE COMPOUNDS ISHIHARA SANGYO KAISHA, LTD. (JP) 2010-06-17 WO disclosed
US-20100099563-A1 HERBICIDAL COMPOSITIONS CONTAINING BENZOYLPYRAZOLE COMPOUNDS ISHIHARA SANGYO KAISHA, LTD. (JP) 2010-04-22 US disclosed
EP-2172104-A1 HERBICIDAL COMPOSITION ISHIHARA SANGYO KAISHA, LTD. (JP) 2010-04-07 EP disclosed
WO-2009142318-A1 PYRAZOLE COMPOUNDS, PROCESS FOR THEIR PRODUCTION AND HERBICIDES CONTAINING THEM ISHIHARA SANGYO KAISHA, LTD. (JP) 2009-11-26 WO disclosed
US-20090286683-A1 BENZOYLPYRAZOLE COMPOUNDS AND HERBICIDES CONTAINING THEM ISHIHARA SANGYO KAISHA, LTD. (JP) 2009-11-19 US disclosed
EP-2106697-A1 HERBICIDAL COMPOSITIONS CONTAINING BENZOYLPYRAZOLE COMPOUNDS ISHIHARA SANGYO KAISHA, LTD. (JP) 2009-10-07 EP disclosed
EP-1963274-A1 BENZOYLPYRAZOLE COMPOUNDS AND HERBICIDES CONTAINING THEM ISHIHARA SANGYO KAISHA, LTD. (JP) 2008-09-03 EP disclosed
WO-2007069771-A1 BENZOYLPYRAZOLE COMPOUNDS AND HERBICIDES CONTAINING THEM ISHIHARA SANGYO KAISHA, LTD. (JP) 2007-06-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230138225-A1 PYRAZOLE CARBOXYLATE ESTER COMPOUND AND USE THEREOF NOTUM, CYP3A5, CYP2E1 SMN1; SMN2 4803/4885RAB9A 1578/4885LMNA 4326/4885
US-20110160062-A1 PYRAZOLE COMPOUNDS, PROCESS FOR THEIR PRODUCTION AND HERBICIDES CONTAINING THEM ARSA, AADAC, PDXK SMN1; SMN2 4560/4885RAB9A 2381/4885LMNA 4746/4885
US-20090286683-A1 BENZOYLPYRAZOLE COMPOUNDS AND HERBICIDES CONTAINING THEM DDT, ABAT, AADAC SMN1; SMN2 4690/4885RAB9A 3024/4885LMNA 4377/4885
US-20100099563-A1 HERBICIDAL COMPOSITIONS CONTAINING BENZOYLPYRAZOLE COMPOUNDS HCN3, CBR3, DDT SMN1; SMN2 3956/4885RAB9A 1994/4885LMNA 4037/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.