Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10385051 | 0.86 | ALOX15 (0.49) | ALDH1A1MAPTHPGDLMNA | |
| SCHEMBL9826852 | 0.78 | CNR1 (0.56) | THRBPOLBCNR1CA1CA2 | |
| SCHEMBL9826567 | 0.76 | THRB (0.54) | THRBPOLBCNR1EPHX2ALDH1A1 | |
| SCHEMBL10384541 | 0.75 | ALOX15 (0.56) | THRBPOLBCNR1EPHX2CA1 | |
| SCHEMBL10483343 | 0.75 | THRB (0.63) | THRBPOLBCNR1EPHX2CA1 | |
| SCHEMBL10411289 | 0.73 | THRB (0.61) | THRBPOLBCNR1EPHX2ALDH1A1 | |
| SCHEMBL10412531 | 0.72 | POLB (0.50) | THRBPOLBCNR1EPHX2ALDH1A1 | |
| SCHEMBL10386151 | 0.71 | ALOX15 (0.71) | CNR1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL10412088 | 0.71 | MAPT (0.56) | THRBPOLBCNR1ALDH1A1MAPT | |
| SCHEMBL9827104 | 0.70 | ALOX15 (0.72) | THRBCNR1EPHX2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4939133-A | N-substituted-2-hydroxy-α-oxo-benzeneacetamides and pharmaceutical compositions having activity as modulators of the arachidonic acid cascade | WARNER-LAMBERT COMPANY (US) | 1990-07-03 | — | — | US | claimed |