SCHEMBL5382852

SCHEMBL5382852

CCc1c(C(=O)O)c(F)c(F)c(C(=O)O)c1C(C)(F)F

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HCAR2 Q8TDS4 1/20 0.32
DHODH Q02127 1/20 0.31
TAS1R3 Q7RTX0 3/20 0.30
TAS1R1 Q7RTX1 3/20 0.30
TAS1R2 Q8TE23 3/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29926635 0.77 SMN1; SMN2 (0.42) PKMSMN1; SMN2HCAR2DHODH
SCHEMBL7862999 0.77 SMN1; SMN2 (0.42) PKMSMN1; SMN2HCAR2DHODH
SCHEMBL10981379 0.74 SMN1; SMN2 (0.39) PKMSMN1; SMN2HCAR2DHODH
SCHEMBL5394517 0.71 LDHA (0.35) PKMSMN1; SMN2HCAR2
SCHEMBL11936748 0.71 SMN1; SMN2 (0.41) PKMSMN1; SMN2HCAR2DHODH
SCHEMBL10386157 0.70 SMN1; SMN2 (0.38) PKMSMN1; SMN2HCAR2
SCHEMBL23609662 0.70 HCAR2 (0.38) PKMSMN1; SMN2HCAR2DHODH
SCHEMBL31542027 0.69 SMN1; SMN2 (0.41) SMN1; SMN2
SCHEMBL7596490 0.69 SMN1; SMN2 (0.37) PKMSMN1; SMN2HCAR2
SCHEMBL7863497 0.69 GLRA3 (0.38) PKMSMN1; SMN2TAS1R3TAS1R1TAS1R2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7312366-B2 Preparation of one intermediate for pyrethroids JIANGSU YANGONG CHEMICAL CO., LTD. (CN) 2007-12-25 US disclosed
US-20070055075-A1 Preparation of one intermediate for pyrethroids JIANGSU YANGNONG CHEMICAL CO., LTD. (CN) 2007-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070055075-A1 Preparation of one intermediate for pyrethroids CYP4F2, CYP4F3, CYP4F12 PKM 2915/4885SMN1; SMN2 3131/4885HCAR2 2664/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.