Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ATIC | P31939 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SLC16A3 | O15427 | 3/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10389247 | 0.91 | PLAU (0.45) | PLAUMEN1KMT2AGLO1TDP1 | |
| SCHEMBL10388956 | 0.81 | PLAU (0.47) | PLAUMEN1KMT2AGLO1TDP1 | |
| SCHEMBL9806959 | 0.81 | HSP90AA1 (0.47) | MEN1KMT2ATDP1CYP2C9CYP2C19 | |
| SCHEMBL10389258 | 0.75 | ALDH1A1 (0.54) | CYP2C9CYP2C19HSD17B10ALDH1A1 | |
| SCHEMBL10389342 | 0.74 | KMT2A (0.58) | PLAUMEN1KMT2ATDP1AGTR1 | |
| SCHEMBL1030801 | 0.71 | SNCA (0.51) | MEN1KMT2ATDP1CYP2C9CYP2C19 | |
| SCHEMBL10389254 | 0.71 | DNMT1 (0.60) | MEN1KMT2AMAPT | |
| SCHEMBL9681117 | 0.71 | ALDH1A1 (0.47) | MEN1KMT2ATDP1CYP2C9ATIC | |
| SCHEMBL10389380 | 0.69 | LMNA (0.69) | MEN1KMT2ACYP2C9CYP2C19HSD17B10 | |
| SCHEMBL10703360 | 0.68 | TTR (0.65) | MEN1KMT2ATDP1CYP2C9ATIC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4918183-A | Monoazo dyes, process for their preparation, and the use thereof | CIBA-GEIGY CORPORATION (US) | 1990-04-17 | — | — | US | disclosed |