Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | SLC16A3 | O15427 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.43 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10389342 | 0.87 | KMT2A (0.58) | PLAUALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL10389258 | 0.87 | ALDH1A1 (0.54) | ALDH1A1CYP2C9CYP2C19CASP6HSD17B10 | |
| SCHEMBL10389247 | 0.84 | PLAU (0.45) | PLAUALDH1A1MEN1KMT2ASLC16A3 | |
| SCHEMBL10389286 | 0.81 | PLAU (0.43) | PLAUALDH1A1CYP2C9CYP2C19HSD17B10 | |
| SCHEMBL9806959 | 0.75 | HSP90AA1 (0.47) | ALDH1A1CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL10389380 | 0.75 | LMNA (0.69) | ALDH1A1CYP2C9CYP2C19HSD17B10MEN1 | |
| SCHEMBL10390202 | 0.72 | LMNA (0.50) | ALDH1A1CYP2C9CYP2C19CASP6HSD17B10 | |
| SCHEMBL10388572 | 0.72 | GPR27 (0.54) | ALDH1A1MEN1KMT2ATDP1HDAC1 | |
| SCHEMBL10388565 | 0.71 | CYP2C19 (0.48) | ALDH1A1CYP2C9CYP2C19CASP6HSD17B10 | |
| SCHEMBL9806976 | 0.71 | PGR (0.48) | ALDH1A1MEN1KMT2AHDAC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4918183-A | Monoazo dyes, process for their preparation, and the use thereof | CIBA-GEIGY CORPORATION (US) | 1990-04-17 | — | — | US | disclosed |