Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.45 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 7/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | NEK2 | P51955 | 1/20 | 0.41 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.41 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10389286 | 0.91 | PLAU (0.43) | PLAUSLC16A3MEN1KMT2AAGTR1 | |
| SCHEMBL9806959 | 0.90 | HSP90AA1 (0.47) | MEN1KMT2ACHEK1CDK8NEK2 | |
| SCHEMBL10388956 | 0.84 | PLAU (0.47) | PLAUSLC16A3MEN1KMT2AF2 | |
| SCHEMBL10389258 | 0.79 | ALDH1A1 (0.54) | F2PRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL10389342 | 0.78 | KMT2A (0.58) | PLAUMEN1KMT2AAGTR1KEAP1 | |
| SCHEMBL10389371 | 0.75 | LMNA (0.45) | MEN1KMT2AGLO1ALDH1A1MAPT | |
| SCHEMBL10389380 | 0.72 | LMNA (0.69) | MEN1KMT2AF2PRSS1PRSS2 | |
| SCHEMBL9942077 | 0.71 | RECQL (0.71) | PLAUMEN1KMT2AKEAP1GLO1 | |
| SCHEMBL5415754 | 0.70 | METAP2 (0.44) | CHEK1CDK8NEK2LIMK1KEAP1 | |
| SCHEMBL10390245 | 0.70 | HTR6 (0.63) | MEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4918183-A | Monoazo dyes, process for their preparation, and the use thereof | CIBA-GEIGY CORPORATION (US) | 1990-04-17 | — | — | US | disclosed |