Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.30 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31338754 | 0.85 | KDM4E (0.36) | KDM4ETDP1CYP11B1CYP11B2ENPP2 | |
| SCHEMBL25786873 | 0.85 | KDM4E (0.36) | KDM4ETDP1CYP11B1CYP11B2ENPP2 | |
| SCHEMBL19965605 | 0.81 | KDM4E (0.39) | KDM4ETDP1CYP11B1CYP11B2ENPP2 | |
| SCHEMBL6705973 | 0.81 | TRPV4 (0.52) | KDM4ETDP1CYP11B1CYP11B2ENPP2 | |
| SCHEMBL3368263 | 0.81 | KDM4E (0.39) | KDM4ETDP1CYP11B1CYP11B2ENPP2 | |
| SCHEMBL4007007 | 0.78 | KDM4E (0.52) | KDM4ETDP1CYP11B1CYP11B2ENPP2 | |
| SCHEMBL24147282 | 0.78 | DAO (0.39) | KDM4ETDP1CYP11B1CYP11B2ENPP2 | |
| SCHEMBL10493585 | 0.78 | KDM4E (0.37) | KDM4ETDP1CYP11B1CYP11B2ENPP2 | |
| SCHEMBL1019992 | 0.77 | KDM4E (0.43) | KDM4ETDP1CYP11B1CYP11B2ENPP2 | |
| SCHEMBL8657492 | 0.77 | KDM4E (0.43) | KDM4ETDP1CYP11B1CYP11B2ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4633734-A1 | COMPOUNDS, COMPOSITIONS, AND MEZHODS OF TREATING DISORDERS ASSOCIATED WITH PROTEIN MISFOLDING | Wavebreak Therapeutics, LLC (US) | 2025-10-22 | — | — | EP | disclosed |
| CN-119874565-A | Mono cyano diaryl ethylene preparation method of class compound | 常州大学 | 2025-04-25 | — | — | CN | disclosed |
| WO-2024129881-A1 | COMPOUNDS, COMPOSITIONS, AND MEZHODS OF TREATING DISORDERS ASSOCIATED WITH PROTEIN MISFOLDING | WAVEBREAK THERAPEUTICS LIMITED (US) | 2024-06-20 | — | — | WO | disclosed |
| US-20230247900-A1 | Organic Compound of Formula (I) for Use in Organic Electronic Devices, an Organic Electronic Device Comprising a Compound of Formula (I) and a Display Device Comprising the Organic Electronic Device | NOVALED GMBH (DE) | 2023-08-03 | — | — | US | disclosed |
| US-20230240138-A1 | Organic Electronic Device and Display Device Comprising the Organic Electronic Device as Well as a Composition for Use in Organic Electronic Devices | NOVALED GMBH (DE) | 2023-07-27 | — | — | US | disclosed |
| US-20230240138-A1 | Organic Electronic Device and Display Device Comprising the Organic Electronic Device as Well as a Composition for Use in Organic Electronic Devices | NOVALED GMBH (DE) | 2023-07-27 | — | — | US | disclosed |
| US-20230232712-A1 | Organic Electronic Device and Display Device Comprising the Organic Electronic Device as Well as a Composition for Use in Organic Electronic Devices | NOVALED GMBH (DE) | 2023-07-20 | — | — | US | disclosed |
| US-20230225201-A1 | Organic Light Emitting Diode and Device Comprising the Same | NOVALED GMBH (DE) | 2023-07-13 | — | — | US | disclosed |
| WO-2023046091-A1 | SOLID ELECTROLYTE AND USE THEREOF | 珠海冠宇电池股份有限公司 | 2023-03-30 | — | — | WO | disclosed |
| WO-2023046181-A1 | SOLID ELECTROLYTE AND LITHIUM ION BATTERY COMPRISING SAME | 珠海冠宇电池股份有限公司 | 2023-03-30 | — | — | WO | disclosed |
| US-7910740-B2 | Modulators of amyloid beta | HOFFMANN-LA ROCHE INC. (US) | 2011-03-22 | — | — | US | disclosed |
| EP-2155740-B1 | HETARYLANILINES AS MODULATORS FOR AMYLOID BETA | HOFFMANN LA ROCHE (CH) | 2011-01-26 | — | — | EP | disclosed |
| EP-2257541-A1 | MODULATORS FOR AMYLOID BETA | F. Hoffmann-La Roche AG (CH) | 2010-12-08 | — | — | EP | disclosed |
| EP-2155740-A1 | HETARYLANILINES AS MODULATORS FOR AMYLOID BETA | F. Hoffmann-Roche AG (CH) | 2010-02-24 | — | — | EP | disclosed |
| US-20090215759-A1 | MODULATORS FOR AMYLOID BETA | HOFFMANN-LA ROCHE, INC. | 2009-08-27 | — | — | US | disclosed |
| WO-2009103652-A1 | MODULATORS FOR AMYLOID BETA | F. HOFFMANN-LA ROCHE AG (CH) | 2009-08-27 | — | — | WO | disclosed |
| WO-2008138753-A1 | HETARYLANILINES AS MODULATORS FOR AMYLOID BETA | F. HOFFMANN-LA ROCHE AG (CH) | 2008-11-20 | — | — | WO | disclosed |
| US-20080280948-A1 | MODULATORS OF AMYLOID BETA | F. HOFFMANN-LA ROCHE AG (CH) | 2008-11-13 | — | — | US | disclosed |
| US-6528657-B2 | For use in electroluminescence light emission element and can emit lights of various colors when an energy such as electric energy or electromagnetic energy is applied thereto | TAIHO INDUSTRIES CO., LTD. (JP) | 2003-03-04 | — | — | US | disclosed |
| US-20030023099-A1 | Novel fluorescent carbazole derivative | HIROSE ENGINEERING CO., LTD. (JP) | 2003-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090215759-A1 | MODULATORS FOR AMYLOID BETA | APP, PSEN1, APOB | KDM4E 4071/4885TDP1 263/4885CYP11B1 2133/4885 |
| US-20230247900-A1 | Organic Compound of Formula (I) for Use in Organic Electronic Devices, an Organic Electronic Device Comprising a Compound of Formula (I) and a Display Device Comprising the Organic Electronic Device | AOX1, CYP2C19, CYP2C9 | KDM4E 2865/4885TDP1 2911/4885CYP11B1 88/4885 |
| US-20030023099-A1 | Novel fluorescent carbazole derivative | CBR3, AANAT, SIRT3 | KDM4E 3224/4885TDP1 3928/4885CYP11B1 1005/4885 |
| US-20080280948-A1 | MODULATORS OF AMYLOID BETA | APP, BACE1, BACE2 | KDM4E 3557/4885TDP1 1934/4885CYP11B1 139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.