Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 1/20 | 0.54 |
| ▸ | DRD5 | P21918 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7783645 | 0.81 | DRD1 (0.62) | DRD1DRD5SIGMAR1MEN1KMT2A | |
| SCHEMBL10396300 | 0.80 | HTR1A (0.60) | DRD1DRD5HDAC1HDAC6HTR1A | |
| Hydrochloric Acid SCHEMBL10396301 | 0.80 | DRD1 (0.61) | DRD1DRD5SIGMAR1MEN1KMT2A | |
| SCHEMBL10396293 | 0.78 | TRPV1 (0.58) | DRD1DRD5MEN1KMT2ATRPV1 | |
| SCHEMBL10397351 | 0.76 | PRMT5 (0.56) | DRD1DRD5HDAC1HDAC6MEN1 | |
| SCHEMBL12719663 | 0.76 | ALDH1A1 (0.61) | MEN1KMT2AGAA | |
| Hydrochloric Acid SCHEMBL1625857 | 0.75 | ALDH1A1 (0.60) | MEN1KMT2AGAA | |
| SCHEMBL17517486 | 0.73 | SIGMAR1 (0.68) | SIGMAR1MEN1KMT2AATMRCE1 | |
| SCHEMBL24122147 | 0.73 | SIGMAR1 (0.58) | DRD1DRD5SIGMAR1MEN1KMT2A | |
| SCHEMBL22528276 | 0.73 | SIGMAR1 (0.58) | DRD1DRD5SIGMAR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4977159-A | HYPOTENSIVE AGENTS | SYNTHELABO (FR) | 1990-12-11 | — | — | US | disclosed |