Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 3/20 | 0.56 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.56 |
| ▸ | DRD1 | P21728 | 1/20 | 0.52 |
| ▸ | DRD5 | P21918 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | GPX4 | P36969 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10396300 | 0.84 | HTR1A (0.60) | PRMT5WDR77DRD1DRD5HTR1A | |
| SCHEMBL10396904 | 0.82 | CDK4 (0.64) | HTR1ALMNA | |
| SCHEMBL10396293 | 0.81 | TRPV1 (0.58) | PRMT5WDR77DRD1DRD5TRPV1 | |
| SCHEMBL7783645 | 0.78 | DRD1 (0.62) | DRD1DRD5HTR1AKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL10396301 | 0.77 | DRD1 (0.61) | DRD1DRD5HTR1AKMT2AMEN1 | |
| SCHEMBL6871964 | 0.77 | SIGMAR1 (0.47) | PRMT5WDR77HTR1ALMNA | |
| SCHEMBL11756202 | 0.77 | SMN1; SMN2 (0.58) | PRMT5WDR77SMN1; SMN2HTTFAAH | |
| SCHEMBL10397237 | 0.76 | DRD1 (0.54) | DRD1DRD5HTR1ATRPV1KMT2A | |
| SCHEMBL940424 | 0.76 | LMNA (0.74) | SMN1; SMN2FAAHTRPV1KMT2AGPX4 | |
| SCHEMBL6369610 | 0.74 | HTR1A (0.71) | DRD1DRD5HTR1AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4977159-A | HYPOTENSIVE AGENTS | SYNTHELABO (FR) | 1990-12-11 | — | — | US | disclosed |