Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.58 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.58 |
| ▸ | PI4KA | P42356 | 1/20 | 0.50 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.50 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.50 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10399890 | 0.92 | PI4KA (0.52) | ADORA2AADORA2BPI4KAPI4K2BPI4K2A | |
| SCHEMBL10399501 | 0.86 | ADORA2A (0.76) | ADORA2AADORA2BADORA3ADORA1TSHR | |
| SCHEMBL10399490 | 0.80 | PI4KA (0.57) | ADORA2AADORA2BPI4KAPI4K2BPI4K2A | |
| SCHEMBL10399499 | 0.77 | ADORA2A (0.63) | ADORA2AADORA2BTSHRLMNAMAPT | |
| SCHEMBL10399798 | 0.77 | PGK1 (0.70) | ADORA2AADORA2BADORA3ADORA1TSHR | |
| SCHEMBL10399504 | 0.76 | ADORA2A (0.64) | ADORA2AADORA2BADORA3ADORA1TSHR | |
| SCHEMBL7202938 | 0.75 | ADORA1 (0.66) | ADORA2AADORA2BADORA3ADORA1TSHR | |
| SCHEMBL7202949 | 0.75 | ADORA1 (0.66) | ADORA2AADORA2BADORA3ADORA1TSHR | |
| SCHEMBL10398375 | 0.75 | ADORA2A (0.66) | ADORA2AADORA2BTSHRLMNAMAPT | |
| Hydrochloric Acid SCHEMBL10399464 | 0.75 | ADORA2A (0.63) | ADORA2AADORA2BADORA3ADORA1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4977144-A | ADENOSINE AGONISTS | CIBA-GEIGY CORPORATION (US) | 1990-12-11 | — | — | US | disclosed |
| EP-0354180-A2 | Certain imidazo[4,5-b]pyridine derivatives | CIBA-GEIGY AG (CH) | 1990-02-07 | — | — | EP | disclosed |