Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
| ▸ | PNMT | P11086 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 2/20 | 0.30 |
| ▸ | MAOB | P27338 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13859025 | 0.83 | TSHR (0.39) | TSHRCYP4F2CYP4A11SMN1; SMN2 | |
| SCHEMBL1003365 | 0.80 | TP53 (0.44) | TP53SMN1; SMN2 | |
| SCHEMBL27304037 | 0.78 | TSHR (0.41) | TSHRPNMTMAOAMAOBSMN1; SMN2 | |
| SCHEMBL27258056 | 0.78 | PNMT (0.48) | PNMTSMN1; SMN2 | |
| SCHEMBL28334610 | 0.78 | ALDH1A1 (0.42) | TSHRCYP4F2CYP4A11TP53TDP1 | |
| SCHEMBL49633 | 0.78 | TP53 (0.48) | TSHRPNMTTP53TDP1MAOA | |
| SCHEMBL30730420 | 0.78 | MAOA (0.49) | TSHRTDP1MAOAMAOB | |
| SCHEMBL30206769 | 0.78 | TP53 (0.48) | TSHRPNMTTP53TDP1MAOA | |
| SCHEMBL2568174 | 0.78 | MAOA (0.49) | TSHRTDP1MAOAMAOB | |
| SCHEMBL27480698 | 0.77 | NFE2L2 (0.50) | TSHRMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4933455-A | Lithiated bipyridyl compounds | SHELL OIL COMPANY (US) | 1990-06-12 | — | — | US | disclosed |
| US-4873212-A | Nitrogen-containing bidentate compound immobilized on a solid inorganic carrier | SHELL OIL COMPANY (US) | 1989-10-10 | — | — | US | disclosed |
| US-4873333-A | Nitrogen-containing bidentate compound immobilized on a solid inorganic carrier | SHELL OIL COMPANY (US) | 1989-10-10 | — | — | US | disclosed |