Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | WNK1 | Q9H4A3 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9878208 | 0.91 | PKM (0.54) | PKMALDH1A1TSHRTDP1MAPT | |
| SCHEMBL197978 | 0.86 | PKM (0.67) | PKMALDH1A1TSHRTDP1MAPT | |
| SCHEMBL29516580 | 0.86 | PKM (0.67) | PKMALDH1A1TSHRTDP1MAPT | |
| SCHEMBL1958428 | 0.84 | MAPT (0.71) | PKMALDH1A1TSHRTDP1MAPT | |
| SCHEMBL10485197 | 0.84 | PKM (0.65) | PKMALDH1A1TSHRTDP1MAPT | |
| SCHEMBL10401552 | 0.80 | MAPT (0.47) | PKMALDH1A1TDP1MAPTPOLB | |
| SCHEMBL9817732 | 0.78 | MAPT (0.59) | ALDH1A1TDP1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL9574410 | 0.78 | CA2 (0.49) | ALDH1A1MAPTPOLBKMT2AMAPK1 | |
| SCHEMBL563763 | 0.78 | PKM (0.67) | PKMALDH1A1TSHRTDP1MAPT | |
| SCHEMBL10669752 | 0.78 | CA2 (0.63) | ALDH1A1TSHRMAPTPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992589-A | Substituted phenyl hydroxyethyl sulfones, and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-02-12 | — | — | US | disclosed |