Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 3/20 | 0.44 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2641227 | 0.77 | LTA4H (0.47) | LTA4HLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL975819 | 0.77 | CA12 (0.53) | LTA4HLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL5202843 | 0.77 | LTA4H (0.47) | LTA4HLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL10404569 | 0.77 | KCNH2 (0.46) | CYP1A2CYP2C19MEN1KMT2AAPP | |
| SCHEMBL4365870 | 0.76 | KCNA3 (0.50) | LTA4HLMNACYP2C19HDAC6APP | |
| SCHEMBL2895020 | 0.74 | ADAM17 (0.50) | LTA4HLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL10404489 | 0.74 | LMNA (0.52) | LMNASLC6A2SLC6A3HIF1AMEN1 | |
| SCHEMBL14901603 | 0.72 | LTA4H (0.57) | LTA4HLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL14901605 | 0.72 | GSTP1 (0.58) | LTA4HLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL226548 | 0.72 | LTA4H (0.64) | LTA4HLMNACYP1A2PTGS1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4914206-A | ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-04-03 | — | — | US | disclosed |
| EP-0226896-A2 | Lankacidin derivatives and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1987-07-01 | — | — | EP | disclosed |