Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 7/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | BMP1 | P13497 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | REN | P00797 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3908996 | 0.85 | THRB (0.35) | RORCTDP1LMNAALDH1A1CYP3A4 | |
| SCHEMBL1040689 | 0.84 | REN (0.33) | THRBREN | |
| SCHEMBL1040374 | 0.84 | MMP9 (0.36) | TDP1LMNABMP1ALDH1A1CYP3A4 | |
| SCHEMBL1040326 | 0.83 | REN (0.34) | MAPTTHRBREN | |
| SCHEMBL4537467 | 0.82 | RORC (0.33) | RORCTDP1LMNAALDH1A1CYP3A4 | |
| SCHEMBL1038321 | 0.80 | REN (0.34) | MAPTTHRBREN | |
| SCHEMBL1037840 | 0.78 | REN (0.33) | RORCREN | |
| SCHEMBL3915719 | 0.78 | PKM (0.39) | LMNAALDH1A1CYP3A4MAPTCYP2C19 | |
| SCHEMBL1038318 | 0.78 | REN (0.37) | REN | |
| SCHEMBL1038944 | 0.78 | TDP1 (0.33) | RORCTDP1LMNABMP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049514-B1 | NITRATE ESTERS OF PIPERIDINES | NOVARTIS AG (CH) | 2011-01-26 | — | — | EP | disclosed |