Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.46 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10407445 | 0.89 | RAPGEF4 (0.44) | RAPGEF4MEP1BALDH1A1MAPTHPGD | |
| SCHEMBL10407436 | 0.86 | RAPGEF4 (0.50) | RAPGEF4MEP1BALDH1A1MAPTHPGD | |
| SCHEMBL11775839 | 0.85 | SMN1; SMN2 (0.43) | ALDH1A1MAPTHPGDKMT2ASMN1; SMN2 | |
| SCHEMBL7036105 | 0.83 | MEP1B (0.43) | RAPGEF4MEP1BALDH1A1MAPTHPGD | |
| SCHEMBL4394138 | 0.83 | MEP1B (0.43) | RAPGEF4MEP1BALDH1A1MAPTHPGD | |
| SCHEMBL7034776 | 0.83 | MEP1B (0.46) | RAPGEF4MEP1BALDH1A1MAPTHPGD | |
| SCHEMBL3253706 | 0.82 | MEP1B (0.47) | RAPGEF4MEP1BALDH1A1MAPTHPGD | |
| SCHEMBL28999306 | 0.81 | CA1 (0.48) | ALDH1A1MAPTKMT2ASMN1; SMN2LMNA | |
| SCHEMBL1371763 | 0.81 | CA2 (0.45) | ALDH1A1MAPTKMT2ASMN1; SMN2GAA | |
| SCHEMBL4390836 | 0.80 | ALDH1A1 (0.43) | RAPGEF4MEP1BALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4975516-A | CHAIN EXTENDERS | BAYER AKTIENGESELLSCHAFT (DE) | 1990-12-04 | — | — | US | disclosed |
| EP-0325915-A2 | Diaminoaryl sulfones, process for their preparation and use in the preparation of polyurethane elastomers | BAYER AG (DE) | 1989-08-02 | — | — | EP | disclosed |
| US-3976672-A | INSECTICIDE | UNIROYAL INC. (US) | 1976-08-24 | — | — | US | disclosed |