Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 3/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 7/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28001849 | 0.82 | TRPV1 (0.40) | KDM4EALDH1A1HCRTR2NPC1RAB9A | |
| SCHEMBL30812977 | 0.80 | POLB (0.44) | HTR7SMN1; SMN2KDM4EPKM | |
| SCHEMBL9785817 | 0.80 | POLB (0.44) | HTR7SMN1; SMN2KDM4EPKM | |
| SCHEMBL1845395 | 0.79 | PTGDR2 (0.49) | ENPP2HTR1A | |
| SCHEMBL6799198 | 0.78 | ENPP2 (0.48) | HTR2BSIGMAR1HTR7TMEM97ENPP2 | |
| SCHEMBL9669326 | 0.77 | HTR1A (0.58) | HTR2BSIGMAR1HTR7TMEM97ENPP2 | |
| SCHEMBL25659961 | 0.76 | ENPP2 (0.49) | HTR2BSIGMAR1HTR7TMEM97ENPP2 | |
| SCHEMBL206776 | 0.76 | MTNR1A (0.49) | GABRA1GABRB2MTNR1AHCRTR1HCRTR2 | |
| SCHEMBL9668110 | 0.76 | HTR1A (0.44) | HTR2BSIGMAR1HTR7TMEM97ENPP2 | |
| SCHEMBL5226600 | 0.76 | MTNR1A (0.65) | HTR1AMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4977166-A | ANTIARRHYTHMIC AND ANTIFIBRILLATORY AGENTS | RHONE-POULENC SANTE (FR) | 1990-12-11 | — | — | US | disclosed |